Naphtho[2,1-B]thiophene-1-OL

Base Information

• Chemical Name: Naphtho[2,1-B]thiophene-1-OL
• CAS No.: 60569-00-8
• Molecular Formula: C12H8OS
• Molecular Weight: 200.261
• European Community (EC) Number: 262-305-7
• UNII: 7S26URD97L
• DSSTox Substance ID: DTXSID60209370
• Nikkaji Number: J268.227C
• Wikidata: Q83083645
• Mol file: 60569-00-8.mol

Synonyms:60569-00-8;Naphtho(2,1-b)thiophene-1-ol;NAPHTHO[2,1-B]THIOPHENE-1-OL;EINECS 262-305-7;7S26URD97L;NAPHTHO[2,1-B]THIOPHEN-1-OL;UNII-7S26URD97L;DTXSID60209370

Chemical Property of Naphtho[2,1-B]thiophene-1-OL

Chemical Property:

• Vapor Pressure: 2.42E-07mmHg at 25°C
• Boiling Point: 411°Cat760mmHg
• Flash Point: 202.4°C
• Density: 1.375g/cm³
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 200.02958605
• Heavy Atom Count: 14
• Complexity: 218

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC3=C2C(=CS3)O

Technology Process of Naphtho[2,1-B]thiophene-1-OL

There total 5 articles about Naphtho[2,1-B]thiophene-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-naphthylthio)acetic acid (93-21-0) → naphtho[2,1-b]thiophen-1-ol (60569-00-8)

Guidance literature:

With chloroform; phosphorus pentachloride; Behandeln des erhaltenen <2>Naphthylmercapto-acetylchlorids mit Aluminiumchlorid in Chlorbenzol;

DOI:10.1021/ja01632a017

Reference yield:

1-hydroxy-naphtho[2,1-b]thiophene-2-carboxylic acid → naphtho[2,1-b]thiophen-1-ol (60569-00-8)

Guidance literature:

Reference yield:

1-hydroxy-naphtho[2,1-b]thiophene-2-carboxylic acid → naphtho[2,1-b]thiophen-1-ol (60569-00-8)

Guidance literature:

upstream raw materials:

(2-naphthylthio)acetic acid

carbon disulfide

aluminium trichloride

2-methylthionaphthalene

Downstream raw materials:

1,2-dihydro-naphtho[2,1-b]thiophene-3,3-dioxide

naphtho[2,1-b]thiophene

2-benzylidene-naphtho[2,1-b]thiophen-1-one

2-(4-nitro-benzylidene)-naphtho[2,1-b]thiophen-1-one