2-Morpholin-4-ylpropan-1-ol

Base Information

• Chemical Name: 2-Morpholin-4-ylpropan-1-ol
• CAS No.: 69296-06-6
• Molecular Formula: C7H15NO2
• Molecular Weight: 145.202
• Hs Code.: 2934999090
• European Community (EC) Number: 873-608-4
• DSSTox Substance ID: DTXSID00450743
• Mol file: 69296-06-6.mol

Synonyms:2-morpholin-4-ylpropan-1-ol;69296-06-6;2-(morpholin-4-yl)propan-1-ol;2-Morpholinopropan-1-ol;2-morpholin-4-yl-propanol;SCHEMBL295997;2-Morpholin-4-yl-propan-1-ol;DTXSID00450743;GPRXBRDKYYXGEU-UHFFFAOYSA-N;CEC30649;MFCD12027092;STK503528;AKOS000321545;AKOS016342144;LS-02114;2-MORPHOLIN-4-YLPROPAN-1-OL 95%;BB 0240887;EN300-296385

Chemical Property of 2-Morpholin-4-ylpropan-1-ol

Chemical Property:

• PSA: 32.70000
• LogP: -0.36270
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 145.110278721
• Heavy Atom Count: 10
• Complexity: 91.6

Purity/Quality:

98%min ^*data from raw suppliers

2-Morpholin-4-ylpropan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(CO)N1CCOCC1

Technology Process of 2-Morpholin-4-ylpropan-1-ol

There total 5 articles about 2-Morpholin-4-ylpropan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

morpholine (110-91-8,99108-56-2) + methyloxirane (75-56-9,16033-71-9) → beta-methyl morpholinoethanol (69296-06-6) + 4-(2-hydroxypropyl)morpholine (2109-66-2)

Guidance literature:

In methanol; at 45 ℃; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/S0022-1139(00)80506-0

Reference yield:

2-morpholinopropionic acid methyl ester (110073-17-1) → beta-methyl morpholinoethanol (69296-06-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h;

Reference yield:

2-Amino-1-propanol (6168-72-5) + 3-oxa-1,5-dichloropentane (111-44-4) → beta-methyl morpholinoethanol (69296-06-6)

Guidance literature:

With potassium carbonate; at 150 ℃;

DOI:10.1021/ja01523a036

upstream raw materials:

2-Amino-1-propanol

3-oxa-1,5-dichloropentane

morpholine

methyloxirane