Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxy-

Base Information

• Chemical Name: Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxy-
• CAS No.: 69404-94-0
• Molecular Formula: C14H22O3Si
• Molecular Weight: 266.412
• DSSTox Substance ID: DTXSID60441511
• Nikkaji Number: J796.231B
• Mol file: 69404-94-0.mol

Synonyms:69404-94-0;Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxy-;4-[tert-butyl(dimethyl)silyl]oxy-3-methoxybenzaldehyde;Vanillin, tert-butyldimethylsilyl ether;Methoxy-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-benzaldehyde;4-((tert-Butyldimethylsilyl)oxy)-3-methoxybenzaldehyde;4-[(TERT-BUTYLDIMETHYLSILYL)OXY]-3-METHOXYBENZALDEHYDE;Vanillin, TBDMS derivative;SCHEMBL22428;DTXSID60441511;4-t-butyldimethylsilanyloxy-3-methoxybenzaldehyde;EN300-1706999;3-Methoxy-4-(tert-butyldimethylsiloxy)benzaldehyde;4-(t-butyldimethylsilyloxy)-3-methoxybenzaldehyde

Chemical Property of Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxy-

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 266.13382109
• Heavy Atom Count: 18
• Complexity: 283

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)OC1=C(C=C(C=C1)C=O)OC

Technology Process of Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxy-

There total 4 articles about Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

vanillin (121-33-5,8014-42-4) + tert-butyldimethylsilyl chloride (18162-48-6) → O-tert-butyldimethylsilylvanillin (69404-94-0)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1248/bpb.b12-00605

Reference yield: 99.0%

t-butyldimethylsiyl triflate (69739-34-0) + vanillin (121-33-5,8014-42-4) → O-tert-butyldimethylsilylvanillin (69404-94-0)

Guidance literature:

With 2,6-dimethylpyridine; In dichloromethane; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.3390/molecules14072491

Reference yield: 96.0%

4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-benzaldehyde oxime → O-tert-butyldimethylsilylvanillin (69404-94-0)

Guidance literature:

With Glyoxilic acid; In water; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2004.02.049

upstream raw materials:

vanillin

tert-butyldimethylsilyl chloride

t-butyldimethylsiyl triflate

3,4-dihydroxybenzaldehyde

Downstream raw materials:

benzyl alcohol

capsiate

Vanillyl nonanoate

4-hydroxy-3-methoxybenzyl hexadecanoate