2-(4-Methoxyphenyl)pyrimidine

Base Information

Chemical Name:2-(4-Methoxyphenyl)pyrimidine
CAS No.:69491-44-7
Molecular Formula:C11H10N2O
Molecular Weight:186.213
Hs Code.:
DSSTox Substance ID:DTXSID10449204
Nikkaji Number:J1.225.542J
ChEMBL ID:CHEMBL2392358

Synonyms:2-(4-methoxyphenyl)pyrimidine;CHEMBL2392358;C11H10N2O;69491-44-7;CMC-46-280-F7;2-(p-Anisyl)pyrimidine;SCHEMBL14679265;DTXSID10449204;PDAIFTPWQFGJGD-UHFFFAOYSA-N;KUC104532N;BDBM50435454;NCGC00188827-01

Suppliers and Price of 2-(4-Methoxyphenyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(4-Methoxyphenyl)pyrimidine

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:186.079312947
Heavy Atom Count:14
Complexity:161

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC=CC=N2

Technology Process of 2-(4-Methoxyphenyl)pyrimidine

There total 15 articles about 2-(4-Methoxyphenyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1722-12-9,1195939-87-7
2-chloropyrimidine

: 5720-07-0
4-methoxyphenylboronic acid

: 69491-44-7
2-(4-methoxy-phenyl)-pyrimidine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,4-dioxane; at 90 ℃;
DOI:10.1002/adsc.200900778

Reference yield: 96.0%

: 1722-12-9,1195939-87-7
2-chloropyrimidine

: 104-92-7
1-bromo-4-methoxy-benzene

: 69491-44-7
2-(4-methoxy-phenyl)-pyrimidine

Guidance literature:: 1-bromo-4-methoxy-benzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.833333h;

With zinc dibromide; In tetrahydrofuran; hexane; at -78 - 20 ℃;

2-chloropyrimidine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; Further stages.; Heating;
DOI:10.1039/b205027g

Reference yield: 93.0%

: 51721-68-7
4-methoxybenzamidine hydrochloride

: 289-96-3
1,2,3-triazine

: 69491-44-7
2-(4-methoxy-phenyl)-pyrimidine

Guidance literature:: 4-methoxybenzamidine hydrochloride; With potassium hydroxide; In dichloromethane; water;

1,2,3-triazine; In acetonitrile; at 60 ℃; for 2h; regioselective reaction;
DOI:10.1021/ol2007428