Technology Process of Acetamide,
N-cyclohexyl-2-[(1,2-dihydro-2-oxo-6-quinolinyl)oxy]-N-methyl-
There total 6 articles about Acetamide,
N-cyclohexyl-2-[(1,2-dihydro-2-oxo-6-quinolinyl)oxy]-N-methyl- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
4-methyl-morpholine; isobutyl chloroformate;
In
N,N-dimethyl-formamide;
1.) 3 h, -15 deg C; 2.) overnight, room temp.;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 47 percent / K2CO3, KI / dimethylsulfoxide / 5 h / 70 °C
2: 93 percent / KOH / methanol / 1 h / Heating
3: 26 percent / N-methyl morpholine, isobutyl chloroformiate / dimethylformamide / 1.) 3 h, -15 deg C; 2.) overnight, room temp.
With
4-methyl-morpholine; potassium hydroxide; potassium carbonate; potassium iodide; isobutyl chloroformate;
In
methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 82 percent / aluminium chloride / chlorobenzene / 2 h / 100 - 110 °C
2: 47 percent / K2CO3, KI / dimethylsulfoxide / 5 h / 70 °C
3: 93 percent / KOH / methanol / 1 h / Heating
4: 26 percent / N-methyl morpholine, isobutyl chloroformiate / dimethylformamide / 1.) 3 h, -15 deg C; 2.) overnight, room temp.
With
4-methyl-morpholine; potassium hydroxide; aluminium trichloride; potassium carbonate; potassium iodide; isobutyl chloroformate;
In
methanol; dimethyl sulfoxide; N,N-dimethyl-formamide; chlorobenzene;
