1-benzhydryl-5-methyl-2,4(1H,3H)-pyrimidinedione

Base Information

• Chemical Name: 1-benzhydryl-5-methyl-2,4(1H,3H)-pyrimidinedione
• CAS No.: 696617-65-9
• Molecular Formula: C18H16N2O2
• Molecular Weight: 292.337
• DSSTox Substance ID: DTXSID40394753
• Nikkaji Number: J2.134.900C
• Wikidata: Q82194347

Synonyms:696617-65-9;ST052118;1-benzhydryl-5-methyl-2,4(1H,3H)-pyrimidinedione;DTXSID40394753;STK683224;AKOS005597380;5-Methyl-1-benzhydrylpyrimidine-2,4(1H,3H)-dione;1-(diphenylmethyl)-5-methylpyrimidine-2,4(1H,3H)-dione

Chemical Property of 1-benzhydryl-5-methyl-2,4(1H,3H)-pyrimidinedione

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 292.121177757
• Heavy Atom Count: 22
• Complexity: 442

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CN(C(=O)NC1=O)C(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 1-benzhydryl-5-methyl-2,4(1H,3H)-pyrimidinedione

There total 2 articles about 1-benzhydryl-5-methyl-2,4(1H,3H)-pyrimidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

thymin (65-71-4,28806-14-6,691841-57-3) + Bromodiphenylmethane (776-74-9) → 1-benzhydryl-5-methyl-1H-pyrimidine-2,4-dione (696617-65-9)

Guidance literature:

thymin; With N,O-bis-(trimethylsilyl)-acetamide; In acetonitrile; at 20 ℃;

Bromodiphenylmethane; With iodine; In acetonitrile; Heating;

DOI:10.1021/jo0485076

Reference yield: 80.0%

Bromodiphenylmethane (776-74-9) + 2,4-bis(trimethylsiloxy)-5-methylpyrimidine (7288-28-0) → 1-benzhydryl-5-methyl-1H-pyrimidine-2,4-dione (696617-65-9)

Guidance literature:

With iodine; In 1,2-dichloro-ethane; for 36h; Heating;

DOI:10.1016/j.tet.2005.02.047

Reference yield: 96.0%

1-benzhydryl-5-methyl-1H-pyrimidine-2,4-dione (696617-65-9) + benzyl bromide (100-39-0) → 1-benzhydryl-3-benzylthymine (821795-57-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1021/jo0485076

upstream raw materials:

Bromodiphenylmethane

2,4-bis(trimethylsiloxy)-5-methylpyrimidine

thymin

Downstream raw materials:

1-benzhydryl-3-benzylthymine

(3-benzhydryl-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl)-acetic acid ethyl ester

1-benzhydryl-3-(3-methoxy-benzyl)-5-methyl-1H-pyrimidine-2,4-dione

1-benzhydryl-5-methyl-3-(2-trifluoromethyl-benzyl)-1H-pyrimidine-2,4-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 696617-65-9 2,4(1H,3H)-Pyrimidinedione, 1-(diphenylmethyl)-5-methyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send