[(2-Bromophenyl)methyl](dimethyl)phosphane

Base Information

• Chemical Name: [(2-Bromophenyl)methyl](dimethyl)phosphane
• CAS No.: 70052-69-6
• Molecular Formula: C₉H₁₂BrP
• Molecular Weight: 231.072
• DSSTox Substance ID: DTXSID00499253
• Nikkaji Number: J2.528.567K
• Wikidata: Q82349865

Synonyms:70052-69-6;[(2-Bromophenyl)methyl](dimethyl)phosphane;DTXSID00499253

Chemical Property of [(2-Bromophenyl)methyl](dimethyl)phosphane

Chemical Property:

• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 229.98600
• Heavy Atom Count: 11
• Complexity: 114

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CP(C)CC1=CC=CC=C1Br

Technology Process of [(2-Bromophenyl)methyl](dimethyl)phosphane

There total 3 articles about [(2-Bromophenyl)methyl](dimethyl)phosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

methylmagnesium chloride (676-58-4) + 2-Bromobenzyl-dibromo-phosphine (161331-13-1) → 1-bromo-2-(dimethylphosphinomethyl)benzene (70052-69-6)

Guidance literature:

In tetrahydrofuran; diethyl ether; 1.) -20 deg C to r.t., overnight, 2.) reflux;

Reference yield:

(trimethylsilyl)methylmagnesium chloride (13170-43-9) + methylmagnesium chloride (676-58-4) + 2-Bromobenzyl-dibromo-phosphine (161331-13-1) → 1-bromo-2-(dimethylphosphinomethyl)benzene (70052-69-6) + 2-Bromobenzyl-trimethylsilylmethyl-methyl-phosphine + 2-Bromobenzyl-bis(trimethylsilylmethyl)-methyl-phosphine

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given; 1.) Et₂O, -60 deg C, 25 min, 2.) THF, -60 deg C to r.t.;

Reference yield:

→ 1-bromo-2-(dimethylphosphinomethyl)benzene (70052-69-6)

Guidance literature:

o-Benzylbromid, Mg, Me2PCl;

DOI:10.1002/zaac.19784470105

upstream raw materials:

(trimethylsilyl)methylmagnesium chloride

methylmagnesium chloride

2-Bromobenzyl-dibromo-phosphine

Downstream raw materials:

2-Bromobenzyl-dimethyl-phosphine oxide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 70052-69-6 Phosphine, [(2-bromophenyl)methyl]dimethyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send