N-Phenyl-2-pyridylmethanimine

Base Information

• Chemical Name: N-Phenyl-2-pyridylmethanimine
• CAS No.: 7032-25-9
• Molecular Formula: C12H10N2
• Molecular Weight: 182.225
• Mol file: 7032-25-9.mol

Synonyms:N-((pyridin-2-yl)formylidene)aniline;N-(pyrid-2-ylmethylene)-phenylamine;N-(2-pyridylmethylene) phenyl amine;(2-pyridylmethylidene)(phenyl)amine;N-(2-pyridinylmethylene)phenylamine;(phenyl)(pyridin-2-ylmethylene)amine;

Chemical Property of N-Phenyl-2-pyridylmethanimine

Chemical Property:

• PSA: 25.25000
• LogP: 2.83220

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Phenyl-2-pyridylmethanimine

There total 33 articles about N-Phenyl-2-pyridylmethanimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

pyridine-2-carbaldehyde (1121-60-4) + aniline (62-53-3) → (E)-N-(2-pyridylmethylene)aniline (7032-25-9,40468-86-8,88785-71-1)

Guidance literature:

In toluene; at 20 ℃; for 24h;

DOI:10.1039/b712901g

Reference yield: 41.0%

pyridine-2-carbaldehyde (1121-60-4) + aniline (62-53-3) → 2-(phenyliminomethyl)pyridine (7032-25-9) + N-phenylpyridine-2-methylamine (4329-81-1)

Guidance literature:

With triethylsilane; hydrio-iridium(III) complex; In water; at 50 ℃;

DOI:10.1016/j.tet.2007.11.079

Reference yield:

C19H19N3 → 2-(phenyliminomethyl)pyridine (7032-25-9) + benzylamine (100-46-9)

Guidance literature:

With methanesulfonic acid; In [D₃]acetonitrile; at 20 ℃; for 24h; Equilibrium constant; Molecular sieve;

DOI:10.1021/jacs.5b11361

upstream raw materials:

aniline

pyridine-2-carbaldehyde

2-Hydroxymethylpyridine

pyridine-2-carboxaldehyde dimethyl acetal

Downstream raw materials:

1,3-diphenyl-4-[2]pyridyl-azetidin-2-one

Phenyl-[1-pyridin-2-yl-meth-(Z)-ylidene]-amine

4-Methyl-1-phenyl-6-(2-pyridyl)-5,6-dihydropyridin-2-one

N-(1-(pyridin-2-yl)but-3-enyl)benzenamine

Refernces

• 1、 Vuong, Hien,Klumpp, Douglas A.. "Superelectrophilic Diels–Alder reactions and oxidations leading to heterocyclic biaryl compounds". supporting information. p. 316 - 323. Retrieved 2019/01/18.
• 2、 Biswas, Nandita,Das, Kalicharan,Sardar, Bitan,Srimani, DIpankar. "Acceptorless dehydrogenative construction of CN and CC bonds through catalytic aza-Wittig and Wittig reactions in the presence of an air-stable ruthenium pincer complex". . p. 6501 - 6512. Retrieved 2019/05/24.