2-Hydroxy-4-morpholin-4-yl-benzaldehyde

Base Information

Chemical Name:2-Hydroxy-4-morpholin-4-yl-benzaldehyde
CAS No.:70362-07-1
Molecular Formula:C11H13NO3
Molecular Weight:207.229
Hs Code.:2934999090
DSSTox Substance ID:DTXSID60431174
Wikidata:Q82244992
ChEMBL ID:CHEMBL2181110
Mol file:70362-07-1.mol

Synonyms:2-HYDROXY-4-MORPHOLINOBENZALDEHYDE;70362-07-1;2-Hydroxy-4-morpholin-4-yl-benzaldehyde;2-hydroxy-4-morpholin-4-ylbenzaldehyde;2-hydroxy-4-(morpholin-4-yl)benzaldehyde;CHEMBL2181110;DNA-PK Inhibitor IV;4-morpholinylsalicylaldehyde;SCHEMBL3664146;4-(4-morpholinyl)salicylaldehyde;DTXSID60431174;QOZQSTNLPIFIAO-UHFFFAOYSA-N;4-(4-morpholinyl) salicylaldehyde;4-(4-morpholinyl)-salicylaldehyde;AR3437;BDBM50398037;MFCD00228054;AKOS024389348;AS-45607;PD077332;2-hydroxy-4-morpholin-4-yl-ben zaldehyde;CS-0071285;A914668;F2163-0209

Suppliers and Price of 2-Hydroxy-4-morpholin-4-yl-benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxy-4-morpholinobenzaldehyde
50mg
$ 240.00

Crysdot
2-Hydroxy-4-morpholinobenzaldehyde 95+%
1g
$ 742.00

Chemenu
2-Hydroxy-4-morpholinobenzaldehyde 95%
1g
$ 700.00

Cayman Chemical
DNA-PK Inhibitor IV ≥98%
50mg
$ 146.00

Cayman Chemical
DNA-PK Inhibitor IV ≥98%
25mg
$ 79.00

Cayman Chemical
DNA-PK Inhibitor IV ≥98%
10mg
$ 45.00

AstaTech
2-HYDROXY-4-MORPHOLINOBENZALDEHYDE 95%
1 / G
$ 890.00

AstaTech
2-HYDROXY-4-MORPHOLINOBENZALDEHYDE 95%
0.1 / G
$ 229.00

AstaTech
2-HYDROXY-4-MORPHOLINOBENZALDEHYDE 95%
0.25 / G
$ 356.00

American Custom Chemicals Corporation
2-HYDROXY-4-MORPHOLINOBENZALDEHYDE 95.00%
5G
$ 4183.99

Total 8 raw suppliers

Chemical Property of 2-Hydroxy-4-morpholin-4-yl-benzaldehyde

Chemical Property:

Boiling Point:401.3±45.0 °C(Predicted)
PKA:8.48±0.10(Predicted)
PSA：49.77000
Density:1.272±0.06 g/cm3(Predicted)
LogP:1.10630
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:207.08954328
Heavy Atom Count:15
Complexity:216

Purity/Quality:

97% ^*data from raw suppliers

2-Hydroxy-4-morpholinobenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1C2=CC(=C(C=C2)C=O)O
Description DNA-PK inhibitor IV is an inhibitor of DNA-dependent protein kinase (DNA-PK) with an IC50 value of 400 nM for the DNA-PK-dependent phosphorylation of a p53 peptide substrate. It also inhibits the phosphatidylinositol 3-kinase (PI3K) isoforms p110β, p110δ, and p110γ (IC50s = 2.8, 5.1, and 37 nM, respectively) but not p110α (IC50 = ~10 μM) or class II PI3Ks, PI4Kβ, ATM, ATR, mTOR, CK2, or GRK2 (IC50s = >50 μM). It enhances radiation-induced cytotoxicity of HCT116 cells when used at a concentration of 100 μM.

Technology Process of 2-Hydroxy-4-morpholin-4-yl-benzaldehyde

There total 5 articles about 2-Hydroxy-4-morpholin-4-yl-benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%