Methyl 2-aminopent-4-enoate

Base Information

• Chemical Name: Methyl 2-aminopent-4-enoate
• CAS No.: 70837-19-3
• Molecular Formula: C₆H₁₁NO₂
• Molecular Weight: 129.159
• DSSTox Substance ID: DTXSID40446685
• Nikkaji Number: J1.289.729D
• Mol file: 70837-19-3.mol

Synonyms:methyl 2-aminopent-4-enoate;70837-19-3;2-amino-pent-4-enoic acid methyl ester;methyl 2-amino-4-pentenoate;methyl2-aminopent-4-enoate;SCHEMBL1198196;DTXSID40446685;JHQZRHILTYGZQL-UHFFFAOYSA-N;2-amino-4-pentenoic acid methyl ester;AKOS013465122;SB37373;SB38404;SB38850;FT-0736666;EN300-1298314

Chemical Property of Methyl 2-aminopent-4-enoate

Chemical Property:

• PSA: 52.32000
• LogP: 0.76310
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 129.078978594
• Heavy Atom Count: 9
• Complexity: 112

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-pent-4-enoicacidmethylester 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C(CC=C)N

Technology Process of Methyl 2-aminopent-4-enoate

There total 19 articles about Methyl 2-aminopent-4-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + L-allylglycine (16338-48-0) → methyl (S)-allylglycinate (50299-15-5,70837-19-3,81136-73-4,105929-46-2)

Guidance literature:

With chloro-trimethyl-silane; at 0 - 20 ℃; for 24h;

Reference yield: 95.0%

methanol (67-56-1) + rac-allylglycine (1069-48-3,7685-44-1) → allylglycine methyl ester (50299-15-5,70837-19-3,81136-73-4,105929-46-2)

Guidance literature:

methanol; rac-allylglycine; With thionyl chloride;

With triethylamine; Further stages.;

DOI:10.1016/j.tetlet.2003.10.147

Reference yield: 87.0%

methyl 2-[(tert-butoxycarbonyl)amino]pent-4-enoate (106928-50-1) → methyl (S)-allylglycinate (50299-15-5,70837-19-3,81136-73-4,105929-46-2)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 0.166667h;

DOI:10.1016/j.jfluchem.2013.03.011

upstream raw materials:

Methyl 2-<(allyloxycarbonyl)amino>-2-methoxyacetate

Methyl 2-(benzhydrylideneamino)-4-pentenoate

methanol

rac-allylglycine

Downstream raw materials:

rac-allylglycine

methyl 2-[(tert-butoxycarbonyl)amino]pent-4-enoate

2-(Toluene-4-sulfonylamino)pent-4-enoic acid methyl ester

2-(4-nitrobenzenesulfonylamino)pent-4-enoic acid methyl ester