Ethyl 5-amino-1-methyl-1H-indole-2-carboxylate

Base Information

Chemical Name:Ethyl 5-amino-1-methyl-1H-indole-2-carboxylate
CAS No.:71056-58-1
Molecular Formula:C12H14N2O2
Molecular Weight:218.255
Hs Code.:
DSSTox Substance ID:DTXSID90465442
Wikidata:Q72486995
Mol file:71056-58-1.mol

Synonyms:71056-58-1;ETHYL 5-AMINO-1-METHYL-1H-INDOLE-2-CARBOXYLATE;ETHYL 5-AMINO-1-METHYLINDOLE-2-CARBOXYLATE;Ethyl 5-amino-1-methyl-indole-2-carboxylate;SCHEMBL1173839;DTXSID90465442;WPRKJQVJYKGTLF-UHFFFAOYSA-N;AKOS005137874;ethyl 5-amino-1-methyl-2-indolecarboxylate;CS-0455066;FT-0735829;A837059;n-methyl-5-aminoindole2-carboxylic acid ethyl ester;5-amino-1-methyl-indole-2-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 5-amino-1-methyl-1H-indole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of Ethyl 5-amino-1-methyl-1H-indole-2-carboxylate

Chemical Property:

Vapor Pressure:9.17E-07mmHg at 25°C
Melting Point:79-80℃
Boiling Point:404.8oC at 760 mmHg
Flash Point:198.6oC
PSA：57.25000
Density:1.22g/cm3
LogP:2.51840
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:218.105527694
Heavy Atom Count:16
Complexity:270

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC2=C(N1C)C=CC(=C2)N

Technology Process of Ethyl 5-amino-1-methyl-1H-indole-2-carboxylate

There total 2 articles about Ethyl 5-amino-1-methyl-1H-indole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 71056-58-1
5-amino-1-methyl-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; for 3h;

Reference yield:

: 71056-57-0
ethyl 1-methyl-5-nitro-1H-indole-2-carboxylate

: 71056-58-1
5-amino-1-methyl-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: With ammonium formate; palladium; In ethanol; water;

Reference yield: 91.0%

: 1224719-48-5
2-fluoro-4-[(2S)-tetrahydrofuran-2-ylmethoxy]benzoic acid

: 71056-58-1
5-amino-1-methyl-1H-indole-2-carboxylic acid ethyl ester

: 1314128-02-3
ethyl 5-[({2-fluoro-4-[(2S)-tetrahydrofuran-2-ylmethoxy]phenyl}carbonyl)amino]-1-methyl-1H-indole-2-carboxylate

Guidance literature:: 2-fluoro-4-[(2S)-tetrahydrofuran-2-ylmethoxy]benzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; at 20 ℃; for 2h;

5-amino-1-methyl-1H-indole-2-carboxylic acid ethyl ester; With triethylamine; In tetrahydrofuran; at 20 ℃;