1,3,2-Dioxaphosphorinane, 2-phenoxy-, 2-oxide

Base Information

• Chemical Name: 1,3,2-Dioxaphosphorinane, 2-phenoxy-, 2-oxide
• CAS No.: 711-07-9
• Molecular Formula: C9H11O4P
• Molecular Weight: 214.158
• DSSTox Substance ID: DTXSID30436459
• Nikkaji Number: J1.649.143H,J801.685B
• Wikidata: Q82251727
• Mol file: 711-07-9.mol

Synonyms:1,3,2-Dioxaphosphorinane, 2-phenoxy-, 2-oxide;711-07-9;SCHEMBL3453447;DTXSID30436459;2-Phenoxy-1,3,2-dioxaphosphorinane 2-oxide;Phosphoric acid, cyclic trimethylene phenyl ester;1,3-Propanediol 1,3-phosphoric acid phenyl ester

Chemical Property of 1,3,2-Dioxaphosphorinane, 2-phenoxy-, 2-oxide

Chemical Property:

• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 214.03949583
• Heavy Atom Count: 14
• Complexity: 215

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1COP(=O)(OC1)OC2=CC=CC=C2

Technology Process of 1,3,2-Dioxaphosphorinane, 2-phenoxy-, 2-oxide

There total 7 articles about 1,3,2-Dioxaphosphorinane, 2-phenoxy-, 2-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Phenoxy-1,3,2-dioxaphosphorianan (1078-57-5) → 2-oxo-2-phenoxy-1,3,2-dioxaphosphorinane (711-07-9)

Guidance literature:

With manganese(IV) oxide; benzene;

DOI:10.1039/jr9570001109

Reference yield:

phosphoric acid-(3-hydroxy-propyl ester)-diphenyl ester (100974-47-8) → 2-oxo-2-phenoxy-1,3,2-dioxaphosphorinane (711-07-9)

Guidance literature:

With pyridine;

DOI:10.1021/ja01559a054

Reference yield:

chlorophosphoric acid diphenyl ester (2524-64-3) → 2-oxo-2-phenoxy-1,3,2-dioxaphosphorinane (711-07-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: aqueous pyridine

With pyridine;

DOI:10.1021/ja01559a054

upstream raw materials:

2-Phenoxy-1,3,2-dioxaphosphorianan

phosphoric acid-(3-hydroxy-propyl ester)-diphenyl ester

O-phenyl phosphorodichloridate

trimethyleneglycol

Downstream raw materials:

Ammonium (3-hydroxypropyl), trimethyl hydroxide phenyl hydrogen phosphate, innersalt

Refernces

• 1、 Corriu, R.J.P.. "NUCLEOPHILIC SUBSTITUTIONS AT SILICON AND PHOSPHORUS. A COMPARISON OF CONTROLLING FACTORS". . p. 1 - 12. Retrieved 2007/10/02.
• 2、 Corriu, Robert J.P.,Lanneau, Gerard F.,Leclercq, Dominique. "SILICON-PHOSPHORUS ANALOGIES. RATE CONTROLLING FACTORS IN SN2(P) REACTIONS. INFLUENCE OF THE NUCLEOPHILE FOR A GIVEN STEREOCHEMISTRY.". . p. 4323 - 4326. Retrieved 2007/10/02.