4(1H)-Pyridinone, 1-hydroxy-2-(4-methoxyphenyl)-6-phenyl-

Base Information

• Chemical Name: 4(1H)-Pyridinone, 1-hydroxy-2-(4-methoxyphenyl)-6-phenyl-
• CAS No.: 71637-94-0
• Molecular Formula: C₁₈H₁₅NO₃
• Molecular Weight: 293.322
• Mol file: 71637-94-0.mol

Synonyms:

Chemical Property of 4(1H)-Pyridinone, 1-hydroxy-2-(4-methoxyphenyl)-6-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4(1H)-Pyridinone, 1-hydroxy-2-(4-methoxyphenyl)-6-phenyl-

There total 6 articles about 4(1H)-Pyridinone, 1-hydroxy-2-(4-methoxyphenyl)-6-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-methoxyphenyl)ethanone (100-06-1) → 1-hydroxy-2-(4-methoxy-phenyl)-6-phenyl-1H-pyridin-4-one (71637-94-0)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium ethylate; diethyl ether

2: aq.-ethanolic KOH-solution

3: ethanol; sodium acetate; water; hydroxylamine hydrochloride

With potassium hydroxide; diethyl ether; ethanol; hydroxylamine hydrochloride; water; sodium ethanolate; sodium acetate;

DOI:10.1039/jr9540001755

Reference yield:

2-(4-methoxyphenyl)-6-phenyl-4H-pyran-4-one (14116-43-9) → 1-hydroxy-2-(4-methoxy-phenyl)-6-phenyl-1H-pyridin-4-one (71637-94-0)

Guidance literature:

With ethanol; hydroxylamine hydrochloride; water; sodium acetate;

DOI:10.1039/jr9540001755

Reference yield:

5-(4-methoxyphenyl)-1-phenylpent-1-yne-3,5-dione (107451-78-5) → 1-hydroxy-2-(4-methoxy-phenyl)-6-phenyl-1H-pyridin-4-one (71637-94-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic KOH-solution

2: ethanol; sodium acetate; water; hydroxylamine hydrochloride

With potassium hydroxide; ethanol; hydroxylamine hydrochloride; water; sodium acetate;

DOI:10.1039/jr9540001755

upstream raw materials:

2-(4-methoxyphenyl)-6-phenyl-4H-pyran-4-one

ethanol

hydroxylamine

sodium acetate