Difunctional alpha hydroxy ketone

Base Information

• Chemical Name: Difunctional alpha hydroxy ketone
• CAS No.: 71868-15-0
• Molecular Formula: C20H22O5
• Molecular Weight: 342.392
• Mol file: 71868-15-0.mol

Synonyms:2-hydroxy-1-{4-[4-(2-hydroxy-2-methyl-propionyl)-phenoxy]-phenyl}-2-methyl-propan-1-one;1,1'-(4,4'-oxybis(4,1-phenylene))bis(2-hydroxy-2-methylpropan-1-one);1-Propanone,1,1'-(oxydi-4,1-phenylene)bis[2-hydroxy-2-methyl;

Chemical Property of Difunctional alpha hydroxy ketone

Chemical Property:

• Boiling Point: 514.2±45.0 °C(Predicted)
• PKA: 12.58±0.29(Predicted)
• PSA: 83.83000
• Density: 1.204±0.06 g/cm3(Predicted)
• LogP: 3.38610

Purity/Quality:

99%,98%, ^*data from raw suppliers

1-Propanone,1,1'-(oxydi-4,1-phenylene)bis(2-hydroxy-2-methyl- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Difunctional alpha-hydroxyl ketone is a ketone derivative, which can be used as a photoinitiator.

Technology Process of Difunctional alpha hydroxy ketone

There total 8 articles about Difunctional alpha hydroxy ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

bis<4-(2-bromisobutyryl)phenyl> ether (157891-77-5) → 2-hydroxy-1-{4-[4-(2-hydroxy-2-methylpropionyl)phenoxy]phenyl}-2-methyl-propan-1-one (71868-15-0)

Guidance literature:

bis<4-(2-bromisobutyryl)phenyl> ether; With sodium disulfite; In water; at 85 ℃; for 0.166667h;

With sodium hydroxide; In water; isopropyl alcohol; for 0.25h; Product distribution / selectivity; Reflux;

Reference yield: 68.0%

2-chloro-1-{4-[4-(2-chloro-2-methyl-propionyl)-phenoxy]-phenyl}-2-methyl-propan-1-one (649757-85-7) → 2-hydroxy-1-{4-[4-(2-hydroxy-2-methylpropionyl)phenoxy]phenyl}-2-methyl-propan-1-one (71868-15-0)

Guidance literature:

With sodium hydroxide; In water; isopropyl alcohol; at 80 ℃; for 0.25h; Product distribution / selectivity;

Reference yield:

1,1'-(oxybis(4,1-phenylene))bis(1-bromo-2-methylpropan-2-ol) → 2-hydroxy-1-{4-[4-(2-hydroxy-2-methylpropionyl)phenoxy]phenyl}-2-methyl-propan-1-one (71868-15-0)

Guidance literature:

1,1'-(oxybis(4,1-phenylene))bis(1-bromo-2-methylpropan-2-ol); With water; at 100 ℃; for 1h;

With dihydrogen peroxide; for 6h; Cooling with ice; Irradiation;

upstream raw materials:

bis<4-(2-bromisobutyryl)phenyl> ether

2-chloro-1-{4-[4-(2-chloro-2-methyl-propionyl)-phenoxy]-phenyl}-2-methyl-propan-1-one

diphenylether

1,1'-oxybis(4-methyl-benzene)

Downstream raw materials:

bis<4-(2-bromisobutyryl)phenyl> ether

C₃₈H₅₀O₁₃

Refernces

• 1、 -. "PROCESS FOR PREPARING ARYL KETONE". . . Retrieved 2017/06/12.
• 2、 -. "PROCESS FOR THE PREPARATION OF AROMATIC ALPHA-HYDROXY KETONES". Page/Page column 5. . Retrieved 2011/04/18.