2-Butyl-1H-imidazole-4,5-dicarboxylic acid

Base Information

Chemical Name:2-Butyl-1H-imidazole-4,5-dicarboxylic acid
CAS No.:71998-99-7
Molecular Formula:C9H12N2O4
Molecular Weight:212.205
Hs Code.:
DSSTox Substance ID:DTXSID40597606
Wikidata:Q82493223

Synonyms:2-Butyl-1H-imidazole-4,5-dicarboxylic acid;71998-99-7;2-butylimidazole-4,5-dicarboxylic acid;Oprea1_378300;SCHEMBL7300490;DTXSID40597606;2-n-butylimidazole-4,5-dicarboxylic acid

Suppliers and Price of 2-Butyl-1H-imidazole-4,5-dicarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Butyl-1H-imidazole-4,5-dicarboxylic acid

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:212.07970687
Heavy Atom Count:15
Complexity:257

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC1=NC(=C(N1)C(=O)O)C(=O)O

Technology Process of 2-Butyl-1H-imidazole-4,5-dicarboxylic acid

There total 1 articles about 2-Butyl-1H-imidazole-4,5-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 58954-23-7
2-propyl-1H-imidazole-4,5-dicarboxylic acid

: 71998-99-7
2-n-butylimidazole-4,5-dicarboxylic acid

Guidance literature:

Reference yield:

: 71998-99-7
2-n-butylimidazole-4,5-dicarboxylic acid

: 2-butyl-1-[(2'-carboxybiphenyl-4-yl)methyl]-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / HCl / Ambient temperature

2: 78 percent / diethyl ether; CH₂Cl₂ / 1 h / 10 - 15 °C

3: 1.) t-BuOK / 1.) DMA, 0 deg C, 10 min, 2.) DMA, RT, 1 h

4: 99 percent / HCl / dioxane / 16 h / Ambient temperature

5: 81 percent / LiOH*H₂O / dioxane; H₂O / 5 h / Ambient temperature

With hydrogenchloride; lithium hydroxide; potassium tert-butylate; In 1,4-dioxane; diethyl ether; dichloromethane; water;
DOI:10.1021/jm950450f

Reference yield:

: 71998-99-7
2-n-butylimidazole-4,5-dicarboxylic acid

: 144689-19-0
ethyl 2-butyl-1-[(2'-carboxybiphenyl-4-yl)methyl]-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / HCl / Ambient temperature

2: 78 percent / diethyl ether; CH₂Cl₂ / 1 h / 10 - 15 °C

3: 1.) t-BuOK / 1.) DMA, 0 deg C, 10 min, 2.) DMA, RT, 1 h

4: 99 percent / HCl / dioxane / 16 h / Ambient temperature

With hydrogenchloride; potassium tert-butylate; In 1,4-dioxane; diethyl ether; dichloromethane;
DOI:10.1021/jm950450f