Benzene, 1-methoxy-4-[(1-methylethyl)sulfinyl]-

Base Information

• Chemical Name: Benzene, 1-methoxy-4-[(1-methylethyl)sulfinyl]-
• CAS No.: 7205-71-2
• Molecular Formula: C₁₀H₁₄O₂S
• Molecular Weight: 198.286
• Mol file: 7205-71-2.mol

Synonyms:

Chemical Property of Benzene, 1-methoxy-4-[(1-methylethyl)sulfinyl]-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 1-methoxy-4-[(1-methylethyl)sulfinyl]-

There total 10 articles about Benzene, 1-methoxy-4-[(1-methylethyl)sulfinyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-methoxy-4-<(1-methylethyl)thio>-benzene (7205-61-0) → isopropyl (4-methoxyphenyl) sulfoxide (138723-23-6,138723-24-7,7205-71-2)

Guidance literature:

With 1H-imidazole; dihydrogen peroxide; FeTPPSCl; In acetonitrile; at 25 ℃; for 1h; pH=3;

DOI:10.1039/b209004j

Reference yield: 35.0%

3-(isopropylsulfinyl)propionic acid tert-butyl ester (911820-11-6) + para-iodoanisole (696-62-8) → isopropyl (4-methoxyphenyl) sulfoxide (138723-23-6,138723-24-7,7205-71-2)

Guidance literature:

With potassium hydroxide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In water; toluene; at 70 ℃; for 2h;

DOI:10.1021/ol062315a

Reference yield:

1-methoxy-4-<(1-methylethyl)thio>-benzene (7205-61-0) → (+)-(R)-isopropyl (4-methoxyphenyl) sulfoxide (7205-71-2,138723-23-6,138723-24-7) + (-)-(S)-isopropyl (4-methoxyphenyl) sulfoxide (7205-71-2,138723-24-7,138723-23-6)

Guidance literature:

With (3'S,2R)-(-)-N-(phenylsulfonyl)(3,3-dichlorocamphoryl)oxaziridine; In dichloromethane; at 20 ℃; for 4h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/ja00030a045

upstream raw materials:

1-methoxy-4-<(1-methylethyl)thio>-benzene

3-(isopropylsulfinyl)propionic acid tert-butyl ester

para-iodoanisole

2-iodo-propane

Downstream raw materials:

(+)-(R)-isopropyl (4-methoxyphenyl) sulfoxide

(-)-(S)-isopropyl (4-methoxyphenyl) sulfoxide

isopropenyl 4-methoxyphenyl sulfide

Refernces

• 1、 Kobayashi, Kazuhiro,Shirai, Yuu,Fukamachi, Shuhei,Konishi, Hisatoshi. "Synthesis of 1-(1-arylsulfanylalkyl)indoles and 2,2-bis[1-(1-arylsulfanylalkyl)indol-3-yl]propanes by acid-catalyzed reactions of indoles with aryl vinyl sulfides". body text. p. 433 - 439. Retrieved 2010/09/05.
• 2、 Maitro, Guillaume,Vogel, Sophie,Prestat, Guillaume,Madec, David,Poli, Giovanni. "Aryl sulfoxides via palladium-catalyzed arylation of sulfenate anions". . p. 5951 - 5954. Retrieved 2007/10/03.