Prop-2-en-1-yl 2-[(furan-2-yl)methylidene]-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate

Base Information

• Chemical Name: Prop-2-en-1-yl 2-[(furan-2-yl)methylidene]-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
• CAS No.: 6997-65-5
• Molecular Formula: C23H20N2O4S2
• Molecular Weight: 148.987
• DSSTox Substance ID: DTXSID40410043
• Mol file: 6997-65-5.mol

Synonyms:6997-65-5;DTXSID40410043;Prop-2-en-1-yl 2-[(furan-2-yl)methylidene]-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate

Chemical Property of Prop-2-en-1-yl 2-[(furan-2-yl)methylidene]-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate

Chemical Property:

• Vapor Pressure: 6.31E-14mmHg at 25°C
• Boiling Point: 590.7°Cat760mmHg
• Flash Point: 311°C
• Density: 1.33g/cm³
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 7
• Exact Mass: 452.08644947
• Heavy Atom Count: 31
• Complexity: 843

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(N2C(=O)C(=CC3=CC=CO3)SC2=N1)C4=CC=C(C=C4)SC)C(=O)OCC=C

Technology Process of Prop-2-en-1-yl 2-[(furan-2-yl)methylidene]-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate

There total 3 articles about Prop-2-en-1-yl 2-[(furan-2-yl)methylidene]-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trimethylsilyl methacrylate (13688-56-7) → methacrylic acid bromide (6997-65-5)

Guidance literature:

With dibromotriphenylphosphorane; In dichloromethane; at 15 ℃; for 0.166667h;

Reference yield:

tert-butyldimethylsilyl 2-methylacrylate (105040-99-1) + dibromotriphenylphosphorane (1034-39-5) → methacrylic acid bromide (6997-65-5)

Guidance literature:

In dichloromethane; Ambient temperature;

DOI:10.1021/jo00375a034

Reference yield:

Methacryloyl chloride (920-46-7,26937-45-1) → methacrylic acid bromide (6997-65-5)

Guidance literature:

With phosphorus tribromide;

DOI:10.1016/0584-8539(75)80019-5

upstream raw materials:

Methacryloyl chloride

trimethylsilyl methacrylate

tert-butyldimethylsilyl 2-methylacrylate

dibromotriphenylphosphorane

Downstream raw materials:

isopropyl methacrylate