5,6,8-Trifluoroquinoline

Base Information

Chemical Name:5,6,8-Trifluoroquinoline
CAS No.:5280-10-4
Molecular Formula:C26H24ClN3O5
Molecular Weight:183.13
Hs Code.:
DSSTox Substance ID:DTXSID20200782
Nikkaji Number:J1.068.588E
Wikidata:Q83073948
Mol file:5280-10-4.mol

Synonyms:5,6,8-Trifluoroquinoline;5280-10-4;CCRIS 8761;Quinoline, 5,6,8-trifluoro-;SCHEMBL10510901;DTXSID20200782;AKOS033859200;LS-142190;EN300-250465;Z2242045544

Suppliers and Price of 5,6,8-Trifluoroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5,6,8-Trifluoroquinoline

Chemical Property:

Vapor Pressure:3.47E-21mmHg at 25°C
Boiling Point:240.4°Cat760mmHg
Flash Point:99.2°C
Density:1.415g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:183.02958362
Heavy Atom Count:13
Complexity:188

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=CC(=C2F)F)F)N=C1

Technology Process of 5,6,8-Trifluoroquinoline

There total 3 articles about 5,6,8-Trifluoroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 367-34-0
2,4,5-trifluoroaniline

: 56-81-5,25618-55-7,64333-26-2,8013-25-0
glycerol

: 5280-10-4
5,6,8-Trifluoroquinoline

Guidance literature:: With sulfuric acid; sodium 3-nitrobenzenesulfonate sulfuric acid; In water; at 140 ℃;

Reference yield:

: 5280-07-9
5,6,7,8-Tetrafluoroquinoline

: 5,7,8-trifluoroquinoline

: 5280-10-4
5,6,8-Trifluoroquinoline

Guidance literature:: 5,6,7,8-Tetrafluoroquinoline; With hydrazine hydrate; In 1,4-dioxane; for 6h; Reflux;

With copper(ll) sulfate pentahydrate; rochelle salt; sodium hydroxide; In water; for 0.666667h; Reflux;
DOI:10.1007/s11172-009-0134-z