2-Phenylbenzimidazole-4-carboxamide

Base Information

Chemical Name:2-Phenylbenzimidazole-4-carboxamide
CAS No.:72470-44-1
Molecular Formula:C14H11N3O
Molecular Weight:237.261
Hs Code.:
DSSTox Substance ID:DTXSID30445425
Wikidata:Q82263815
Pharos Ligand ID:CCJ5TCYNUATQ
ChEMBL ID:CHEMBL81723

Synonyms:2-phenylbenzimidazole-4-carboxamide;72470-44-1;CHEMBL81723;2-phenyl-1H-benzo[d]imidazole-4-carboxamide;SCHEMBL458836;SCHEMBL3585683;BDBM27091;DTXSID30445425;OBBJGEVEIULNEO-UHFFFAOYSA-N;2-phenyl-1H-1,3-benzodiazole-4-carboxamide;phenyl-containing benzimidazole carboxamide, 2b

Suppliers and Price of 2-Phenylbenzimidazole-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Phenylbenzimidazole-4-carboxamide

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:237.090211983
Heavy Atom Count:18
Complexity:314

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC3=C(C=CC=C3N2)C(=O)N

Technology Process of 2-Phenylbenzimidazole-4-carboxamide

There total 11 articles about 2-Phenylbenzimidazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 66630-72-6
2-Phenyl-4-benzimidazolylcarboxylic acid

: 72470-44-1
NU₁₀₇₀

Guidance literature:: With ammonium hydroxide; thionyl chloride; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield:

: 266993-72-0
3-carbamoylbenzene-1,2-diaminium dichloride

: 100-52-7
benzaldehyde

: 72470-44-1
NU₁₀₇₀

Guidance literature:: 3-carbamoylbenzene-1,2-diaminium dichloride; With potassium hydroxide; In ethanol; at 20 ℃; for 0.0833333h;

benzaldehyde; With acetic acid; In ethanol; for 0.5h;

With ammonia; more than 3 stages;

Reference yield:

: 606-18-8
3-nitroanthranilic acid

: 72470-44-1
NU₁₀₇₀

Guidance literature:: Multi-step reaction with 4 steps

1: 66 percent / H₂ / 10percent Pd/C / methanol / 760.05 Torr

2: 20 percent / PPA / 1 h / 150 - 160 °C

3: SOCl₂ / tetrahydrofuran; dimethylformamide / 20 °C

4: conc. aq. NH₃ / tetrahydrofuran; dimethylformamide

With ammonium hydroxide; thionyl chloride; hydrogen; 10percent Pd/C; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm000950v