1-(2-Hydroxy-5-methylphenyl)-2,2-dimethylpropan-1-one

Base Information

Chemical Name:1-(2-Hydroxy-5-methylphenyl)-2,2-dimethylpropan-1-one
CAS No.:72569-13-2
Molecular Formula:C12H16O2
Molecular Weight:192.258
Hs Code.:
DSSTox Substance ID:DTXSID80501328
Nikkaji Number:J3.146.157J
Wikidata:Q82353637

Synonyms:1-(2-hydroxy-5-methylphenyl)-2,2-dimethylpropan-1-one;72569-13-2;1-(2-hydroxy-5-methylphenyl)-2,2-dimethyl-1-propanone;SCHEMBL26054350;DTXSID80501328;AKOS011666428;CS-0272426;EN300-1276409

Suppliers and Price of 1-(2-Hydroxy-5-methylphenyl)-2,2-dimethylpropan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(2-Hydroxy-5-methylphenyl)-2,2-dimethylpropan-1-one

Chemical Property:

Boiling Point:51 °C(Press: 0.3 Torr)
PSA：37.30000
Density:1.037±0.06 g/cm3(Predicted)
LogP:2.92940
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:192.115029749
Heavy Atom Count:14
Complexity:215

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)O)C(=O)C(C)(C)C

Technology Process of 1-(2-Hydroxy-5-methylphenyl)-2,2-dimethylpropan-1-one

There total 8 articles about 1-(2-Hydroxy-5-methylphenyl)-2,2-dimethylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 50390-49-3
2,2-dimethyl-1-(m-tolyl)propan-1-one

: 72569-13-2
2,2-dimethyl-1-(2-hydroxy-5-methylphenyl)-1-propanone

Guidance literature:: With [bis(acetoxy)iodo]benzene; [Ru(O₂CMes)₂(p-cymene)]; trifluoroacetic acid; trifluoroacetic anhydride; at 120 ℃; for 30h; chemoselective reaction; Sealed tube;
DOI:10.1021/ol302956s

Reference yield: 62.0%

: 87995-48-0
(2-Brom-4-methylphenyl)-pivaloat

: 72569-13-2
2,2-dimethyl-1-(2-hydroxy-5-methylphenyl)-1-propanone

Guidance literature:: With sec.-butyllithium; In tetrahydrofuran; diethyl ether; hexane; at -95 - -78 ℃; for 1h;
DOI:10.1021/jo00378a044

Reference yield:

: 87995-48-0
(2-Brom-4-methylphenyl)-pivaloat

: 106-44-5
p-cresol

: 72569-13-2
2,2-dimethyl-1-(2-hydroxy-5-methylphenyl)-1-propanone

Guidance literature:: With n-butyllithium; ammonium chloride; Yield given. Multistep reaction; 1) THF, hexane, -100 deg C, 2) THF, hexane, r.t.;