Dodecanedioic acid monomethyl ester

Base Information

• Chemical Name: Dodecanedioic acid monomethyl ester
• CAS No.: 3903-40-0
• Molecular Formula: C13H24O4
• Molecular Weight: 244.331
• Hs Code.: 2918990090
• Mol file: 3903-40-0.mol

Synonyms:Dodecanedioicacid, methyl ester (6CI,7CI);Dodecanedioic acid,1-methyl ester;11-Carbomethoxyundecanoic acid;Methyl 11-carboxyundecanoate;Monomethyl1,12-dodecanedioate;Monomethyl dodecanedioate;NSC 29000;

Chemical Property of Dodecanedioic acid monomethyl ester

Chemical Property:

• Vapor Pressure: 5.28E-06mmHg at 25°C
• Melting Point: 51.5-52 °C
• Refractive Index: 1.456
• Boiling Point: 355.3 °C at 760 mmHg
• PKA: 4.78±0.10(Predicted)
• Flash Point: 124.3 °C
• PSA: 63.60000
• Density: 1.013 g/cm³
• LogP: 3.14500
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: DMSO (Slightly, Heated), Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

Dodecanedioic Acid 1-Methyl Ester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Used in cosmetic compositions. Dodecanedioic Acid 1-Methyl Ester is used in cosmetic composition.

Technology Process of Dodecanedioic acid monomethyl ester

There total 8 articles about Dodecanedioic acid monomethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

methanol (67-56-1) + 1,12-dodecanedioic acid (693-23-2) → 12-methoxy-12-oxododecanoic acid (3903-40-0) + dodecanedioic acid dimethyl ester (1731-79-9)

Guidance literature:

With aluminum oxide; at 25 ℃; for 48h; chemoselective reaction; Green chemistry;

DOI:10.1039/c6gc01900e

Reference yield:

cyclododecanone (830-13-7) → 12-hydroxydodecanoic acid (505-95-3) + 1,12-dodecandiol (5675-51-4) + 12-methoxy-12-oxododecanoic acid (3903-40-0)

Guidance literature:

cyclododecanone; With maleic anhydride; dihydrogen peroxide; In water; at 46 - 49 ℃; for 22h;

With hydrogen; In methanol; water; at 230 ℃; for 22h; under 130050 Torr; Autoclave; Inert atmosphere;

Reference yield:

methyl 11-formylundecanoate (2009-59-8) → 12-hydroxydodecanoic acid (505-95-3) + methyl 12-hydroxydodecanoate (71655-36-2) + 1,12-dodecanedioic acid (693-23-2) + 12-methoxy-12-oxododecanoic acid (3903-40-0)

Guidance literature:

With NADH; In aq. phosphate buffer; Kinetics; Microbiological reaction;

DOI:10.1002/adsc.201200958

upstream raw materials:

1,12-dodecanedioic acid

dimethyl sulfate

methyl n-dodecanoate

methyl 11-formylundecanoate

Downstream raw materials:

11-(p-Hydroxybenzoyl)-undecansaeure

Methyl 10-undecenoate

methyl N-[2-(benzyloxy)ethyl]-N-[7-(F-octyl)heptyl]-11-carboxamidoundecanoate

methyl 11-[(4-methoxybenzyloxy)carbamoyl]undecanoate

Refernces

• 1、 Santos, Luciana de á.,Cavalheiro, Alberto J.,Tempone, Andre G.,Correa, Daniela S.,Alexandre, Tatiana R.,Quintiliano, Natalia F.,Rodrigues-Oliveira, AndréF,Oliveira-Silva, Diogo,Martins, Roberto Carlos C.,Lago, Jo?o Henrique G.. "Antitrypanosomal acetylene fatty acid derivatives from the seeds of Porcelia macrocarpa (Annonaceae)". . p. 8168 - 8180. Retrieved 2015/05/20.
• 2、 -. "PROCESS FOR PRODUCING DODECANE-1, 12-DIOL BY REDUCTION OF LAURYL LACTONE PRODUCED FROM THE OXIDATION OF CYCLODODECANONE". Paragraph 00131. . Retrieved 2013/08/15.