Ethyl 2-oxo-2-(pyridin-3-YL)acetate

Base Information

Chemical Name:Ethyl 2-oxo-2-(pyridin-3-YL)acetate
CAS No.:73672-37-4
Molecular Formula:C9H9NO3
Molecular Weight:179.17300
Hs Code.:2933399090
European Community (EC) Number:848-298-9
DSSTox Substance ID:DTXSID20500097
Wikidata:Q82351456
Mol file:73672-37-4.mol

Synonyms:ETHYL 2-OXO-2-(PYRIDIN-3-YL)ACETATE;73672-37-4;ethyl 2-oxo-2-pyridin-3-ylacetate;MFCD09842445;ethyl 2-oxo-2-(3-pyridyl)acetate;ethyl 3-pyridylglyoxylate;ethyl 3-pyridineglyoxylate;SCHEMBL3218011;Ethyl oxo(pyridin-3-yl)acetate;DTXSID20500097;KVEJGPKUSPYFIE-UHFFFAOYSA-N;AKOS006310137;SB13717;3-pyridineacetic acid,a-oxo,ethyl ester;DS-13436;Oxo-pyridin-3-yl-acetic acid ethyl ester;SY104944;ETHYL2-OXO-2-(PYRIDIN-3-YL)ACETATE;EN300-202639;3-PYRIDINEACETIC ACID, A-OXO, ETHYL ESTER;A849267

Suppliers and Price of Ethyl 2-oxo-2-(pyridin-3-YL)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl2-oxo-2-(pyridin-3-yl)acetate
250mg
$ 110.00

Matrix Scientific
Ethyl 2-oxo-2-(pyridin-3-yl)acetate 95+%
5g
$ 1750.00

Matrix Scientific
Ethyl 2-oxo-2-(pyridin-3-yl)acetate 95+%
1g
$ 700.00

Matrix Scientific
Ethyl 2-oxo-2-(pyridin-3-yl)acetate 95+%
250mg
$ 324.00

Crysdot
Ethyl2-oxo-2-(pyridin-3-yl)acetate 98%
5g
$ 495.00

Chemenu
Ethyl2-oxo-2-(pyridin-3-yl)acetate 98%
5g
$ 468.00

American Custom Chemicals Corporation
ETHYL-2-OXO-2-(PYRIDIN-3-YL)ACETATE 95.00%
5MG
$ 504.81

AK Scientific
Ethyl2-oxo-2-(pyridin-3-yl)acetate
5g
$ 799.00

AK Scientific
Ethyl2-oxo-2-(pyridin-3-yl)acetate
250mg
$ 166.00

Total 28 raw suppliers

Chemical Property of Ethyl 2-oxo-2-(pyridin-3-YL)acetate

Chemical Property:

Vapor Pressure:0.003mmHg at 25°C
Boiling Point:284.749oC at 760 mmHg
PKA:2.24±0.10(Predicted)
Flash Point:126.012oC
PSA：56.26000
Density:1.189g/cm3
LogP:0.82740
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:179.058243149
Heavy Atom Count:13
Complexity:203

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2-oxo-2-(pyridin-3-yl)acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=O)C1=CN=CC=C1

Technology Process of Ethyl 2-oxo-2-(pyridin-3-YL)acetate

There total 10 articles about Ethyl 2-oxo-2-(pyridin-3-YL)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 626-55-1,163928-56-1
3-Bromopyridine

: 109-72-8,29786-93-4
n-butyllithium

: 95-92-1
oxalic acid diethyl ester

: 73672-37-4
ethyl 2-oxo-2-(pyridin-3-yl)acetate

Guidance literature:: With hydrogenchloride; sodium chloride; sodium hydrogencarbonate; In diethyl ether;

Reference yield: 39.0%

: 39684-37-2
oxopyridin-3-ylacetic acid

: 64-17-5
ethanol

: 73672-37-4
ethyl 2-oxo-2-(pyridin-3-yl)acetate

Guidance literature:: With hydrogenchloride; for 8h; Heating;
DOI:10.1007/BF00758616

Reference yield: 15.0%

: 626-55-1,163928-56-1
3-Bromopyridine

: 95-92-1
oxalic acid diethyl ester

: 73672-37-4
ethyl 2-oxo-2-(pyridin-3-yl)acetate

Guidance literature:: 3-Bromopyridine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

oxalic acid diethyl ester; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 20h; Inert atmosphere;
DOI:10.1021/ol400769t