2,2-Dibenzylcyclohexan-1-one

Base Information

• Chemical Name: 2,2-Dibenzylcyclohexan-1-one
• CAS No.: 7382-11-8
• Molecular Formula: C20H22O
• Molecular Weight: 278.394
• DSSTox Substance ID: DTXSID50565856
• Nikkaji Number: J544.315F
• Wikidata: Q82451164
• Mol file: 7382-11-8.mol

Synonyms:2,2-Dibenzylcyclohexan-1-one;7382-11-8;DTXSID50565856

Chemical Property of 2,2-Dibenzylcyclohexan-1-one

Chemical Property:

• PSA: 17.07000
• LogP: 4.60130
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 278.167065321
• Heavy Atom Count: 21
• Complexity: 314

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C(=O)C1)(CC2=CC=CC=C2)CC3=CC=CC=C3

Technology Process of 2,2-Dibenzylcyclohexan-1-one

There total 6 articles about 2,2-Dibenzylcyclohexan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + benzyl bromide (100-39-0) → α,α-dibenzylcyclohexanone (7382-11-8)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran;

DOI:10.1016/j.tet.2005.08.076

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + benzyl bromide (100-39-0) → dibenzyl ether (103-50-4) + α,α-dibenzylcyclohexanone (7382-11-8) + 2-benzylcyclohexan-1-one (946-33-8) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With sodium hydroxide; cetyltrimethylammonim bromide; at 25 ℃; for 48h; Further Variations:; Reagents; Temperatures; reaction time; Product distribution;

DOI:10.1002/1521-3765(20021115)8:22<5204::AID-CHEM5204>3.0.CO;2-C

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + benzyl chloride (100-44-7) → dibenzyl ether (103-50-4) + α,α-dibenzylcyclohexanone (7382-11-8) + 2-benzylcyclohexan-1-one (946-33-8) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With sodium hydroxide; cetyltrimethylammonim bromide; at 25 ℃; for 72h; Further Variations:; Reagents; Temperatures; reaction time; Product distribution;

DOI:10.1002/1521-3765(20021115)8:22<5204::AID-CHEM5204>3.0.CO;2-C

upstream raw materials:

cyclohexanone

benzyl bromide

benzyl chloride

Downstream raw materials:

2,2-dibenzyl-6-methyl-cyclohexanone

2,2-Dibenzylcyclohexanone p-toluenesulfonylhydrazone

3,3-Dibenzylcyclohexene

6,6-dibenzylcyclohex-1-enyl trifluoromethanesulfonate