dipropan-2-yl oxopropanedioate

Base Information

• Chemical Name: dipropan-2-yl oxopropanedioate
• CAS No.: 73972-39-1
• Molecular Formula: C9H14O5
• Molecular Weight: 202.207
• Mol file: 73972-39-1.mol

Synonyms:

Chemical Property of dipropan-2-yl oxopropanedioate

Chemical Property:

• Vapor Pressure: 0.0247mmHg at 25°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of dipropan-2-yl oxopropanedioate

There total 5 articles about dipropan-2-yl oxopropanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diisopropyl malonate (13195-64-7) → α,α-dihydroxyl diisopropyl malonate (70841-85-9) + 2-oxo-malonic acid diisopropyl ester (73972-39-1)

Guidance literature:

With ammonium cerium (IV) nitrate; In acetonitrile; at 0 - 20 ℃; for 4h; Overall yield = 72 %;

DOI:10.1016/j.tetlet.2014.01.145

Reference yield:

diisopropyl malonate (13195-64-7) → 2-oxo-malonic acid diisopropyl ester (73972-39-1)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine / 3 h / 20 - 25 °C

2: silver nitrate / acetonitrile; ethanol / 22 h / Heating

With bromine; silver nitrate; In ethanol; acetonitrile;

Reference yield:

diisopropyl bromomalonate (76407-13-1) → 2-oxo-malonic acid diisopropyl ester (73972-39-1)

Guidance literature:

With silver nitrate; In ethanol; acetonitrile; for 22h; Yield given; Heating;

upstream raw materials:

diisopropyl bromomalonate

diisopropyl malonate

diisopropyl 2-(phenylmethylidene)malonate

Refernces

• 1、 Sivan, Akhil,Deepthi, Ani. "Facile synthesis of 1,2,3-tricarbonyls from 1,3-dicarbonyls mediated by cerium(IV) ammonium nitrate". supporting information. p. 1890 - 1893. Retrieved 2014/03/21.
• 2、 Tietze, Lutz F.,Bratz, Matthias. "Dialkyl mesoxalates by ozonolysis of dialkyl benzalmalonates: Dimethyl mesoxalate". . p. 214 - 214. Retrieved 2017/05/06.