Benzamide, N,N-bis([1,1'-biphenyl]-4-yl)-

Base Information

• Chemical Name: Benzamide, N,N-bis([1,1'-biphenyl]-4-yl)-
• CAS No.: 741267-16-3
• Molecular Formula: C31H23NO
• Molecular Weight: 425.53
• DSSTox Substance ID: DTXSID20474840
• Wikidata: Q82304975
• Mol file: 741267-16-3.mol

Synonyms:Benzamide, N,N-bis([1,1'-biphenyl]-4-yl)-;741267-16-3;SCHEMBL3933240;DTXSID20474840

Chemical Property of Benzamide, N,N-bis([1,1'-biphenyl]-4-yl)-

Chemical Property:

• XLogP3: 7.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 425.177964357
• Heavy Atom Count: 33
• Complexity: 544

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)N(C3=CC=C(C=C3)C4=CC=CC=C4)C(=O)C5=CC=CC=C5

Technology Process of Benzamide, N,N-bis([1,1'-biphenyl]-4-yl)-

There total 2 articles about Benzamide, N,N-bis([1,1'-biphenyl]-4-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

4-iodo-biphenyl (1591-31-7) + benzamide (55-21-0,27208-38-4) → N,N-di([1,1'-biphenyl]-4-yl)benzamide (741267-16-3) + N-([1,1'-biphenyl]-4-yl)benzamide (20743-57-1)

Guidance literature:

With bis(tetrapropylammonium) tetraiododicuprate(I); trans-N,N'-dimethyl-1,2-cyclohexanediamine bis-(methanesulfonic acid); caesium carbonate; In 1,4-dioxane; at 130 ℃; for 24h; Overall yield = 70 %; Overall yield = 402 mg; Inert atmosphere;

DOI:10.1021/jo300905w

Reference yield:

4-bromo-1,1'-biphenyl (92-66-0) + benzamide (55-21-0,27208-38-4) → N,N-di([1,1'-biphenyl]-4-yl)benzamide (741267-16-3)

Guidance literature:

With potassium carbonate; copper(l) iodide; In ortho-diethylbenzene; at 200 ℃; for 18h;

Reference yield: 52.0%

N,N-di([1,1'-biphenyl]-4-yl)benzamide (741267-16-3) + C21H15Br (401941-41-1) → C45H33N

Guidance literature:

With potassium hydroxide; copper(l) iodide; In xylene; at 20 - 140 ℃; for 18h;

upstream raw materials:

4-bromo-1,1'-biphenyl

benzamide

4-iodo-biphenyl

Downstream raw materials:

N,N,N',N'-tetra[(1,1'-biphenyl)-4-yl]-(1,1'-biphenyl)-4,4'-diamine

bis(biphenyl-4-yl)amine