N-(tert-Butoxycarbonyl)-L-phenylalanyl-L-leucinamide

Base Information

Chemical Name:N-(tert-Butoxycarbonyl)-L-phenylalanyl-L-leucinamide
CAS No.:74257-73-1
Molecular Formula:C20H31N3O4
Molecular Weight:377.484
Hs Code.:
DSSTox Substance ID:DTXSID90567218
Wikidata:Q82453027

Synonyms:Boc-Phe-Leu-NH2;74257-73-1;N-(tert-Butoxycarbonyl)-L-phenylalanyl-L-leucinamide;SCHEMBL8897141;DTXSID90567218;RAFQNNBXUDRUGK-HOTGVXAUSA-N

Suppliers and Price of N-(tert-Butoxycarbonyl)-L-phenylalanyl-L-leucinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(tert-Butoxycarbonyl)-L-phenylalanyl-L-leucinamide

Chemical Property:

PSA：118.49000
LogP:4.33300
XLogP3:2.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:377.23145648
Heavy Atom Count:27
Complexity:508

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)OC(C)(C)C
Isomeric SMILES:CC(C)C[C@@H](C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)OC(C)(C)C

Technology Process of N-(tert-Butoxycarbonyl)-L-phenylalanyl-L-leucinamide

There total 12 articles about N-(tert-Butoxycarbonyl)-L-phenylalanyl-L-leucinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 687-51-4,13079-20-4,13366-40-0,15893-47-7
H-L-Leu-NH₂

: 81638-94-0
O-(t-butyloxycarbonyl-L-phenylalanyl)-2-pyridylmethylketoxime

: 74257-73-1
tert-butyl ((S)-1-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate

Guidance literature:: With acetic acid; In tetrahydrofuran; at 30 ℃; for 48h;

Reference yield: 89.0%

: 33014-68-5
tert-butoxycarbonyl-L-phenylalanyl-L-leucine

: 74257-73-1
tert-butyl ((S)-1-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate

Guidance literature:: With 1-hydroxy-1H-benzotriazole ammonium salt; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide;
DOI:10.1016/S0223-5234(98)80060-3

Reference yield: 67.0%

: 687-51-4,13079-20-4,13366-40-0,15893-47-7
H-L-Leu-NH₂

: 88830-49-3
Boc-L-Phe-CAM

: 74257-73-1
tert-butyl ((S)-1-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate

Guidance literature:: With phosphate buffer; mercaptoacetic acid; In N,N-dimethyl-formamide; for 0.166667h; Ambient temperature; papaij;
DOI:10.1007/BF00811332