(R)-2-(Benzylamino)propan-1-ol

Base Information

• Chemical Name: (R)-2-(Benzylamino)propan-1-ol
• CAS No.: 74609-49-7
• Molecular Formula: C10H15NO
• Molecular Weight: 165.235
• European Community (EC) Number: 854-456-8
• Nikkaji Number: J1.406.581D
• Mol file: 74609-49-7.mol

Synonyms:(R)-2-(Benzylamino)propan-1-ol;74609-49-7;(2R)-2-(benzylamino)propan-1-ol;1-Propanol, 2-[(phenylmethyl)amino]-, (2R)-;(R)-2-[(Phenylmethyl)amino]-1-propanol;(2R)-2-[(Phenylmethyl)amino]-1-propanol;(2R)-2-[Benzylamino]propan-1-ol;(R)-2-(Benzylamino)-1-propanol;MFCD20441630;SCHEMBL1005591;PJXWCRXOPLGFLX-SECBINFHSA-N;AMY21724;ZCA60949;AKOS027469927;AS-65733;EN300-90176;W12270;A1-00443;Z823499606

Chemical Property of (R)-2-(Benzylamino)propan-1-ol

Chemical Property:

• Vapor Pressure: 0.000848mmHg at 25°C
• PSA: 69.98000
• LogP: 1.15646
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 165.115364102
• Heavy Atom Count: 12
• Complexity: 110

Purity/Quality:

99% ^*data from raw suppliers

(R)-2-(Benzylamino)propan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CO)NCC1=CC=CC=C1
• Isomeric SMILES: C[C@H](CO)NCC1=CC=CC=C1

Technology Process of (R)-2-(Benzylamino)propan-1-ol

There total 9 articles about (R)-2-(Benzylamino)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(R)-2-aminopropan-1-ol (35320-23-1) + benzaldehyde (100-52-7) → (2R)-2-[(phenylmethyl)amino]-1-propanol (74609-49-7,6940-81-4)

Guidance literature:

(R)-2-aminopropan-1-ol; benzaldehyde; In toluene; Reflux;

With hydrogenchloride; sodium tetrahydroborate; In 1,4-dioxane; ethanol; at 0 - 20 ℃; pH=2;

With sodium hydroxide; In water; pH=> 13;

Reference yield:

(R)-2-{[1-Phenyl-meth-(E)-ylidene]-amino}-propan-1-ol (697763-59-0) → (2R)-2-[(phenylmethyl)amino]-1-propanol (74609-49-7,6940-81-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃; for 2h;

DOI:10.1055/s-2002-25766

Reference yield:

C10H15NO2 → (2R)-2-[(phenylmethyl)amino]-1-propanol (74609-49-7,6940-81-4)

Guidance literature:

With sodium cyanoborohydride; In methanol; at 20 ℃;

upstream raw materials:

D-N-benzoylalanine

2-(benzylamino)-1-propanol

(R)-2-{[1-Phenyl-meth-(E)-ylidene]-amino}-propan-1-ol

benzoyl chloride

Downstream raw materials:

(R)-2-aminopropan-1-ol

N-benzyl-N'-[(1R)-2-hydroxy-1-methylethyl]-(2R,3R)-2,3-di-isopropylidenetartramic acid methyl ester

(R)-3-benzyl-4-methyl-1,2,3-oxathiazolidine-2-oxide

(R)-N-benzyl-2-amino-1-fluoropropane