Technology Process of 2,2,10,10-Tetramethyl-6-[(trimethylsilyl)oxy]-3,9-dioxa-2,10-disilaundecane
There total 5 articles about 2,2,10,10-Tetramethyl-6-[(trimethylsilyl)oxy]-3,9-dioxa-2,10-disilaundecane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trimethylsilyl trifluoromethanesulfonate;
In
tetrahydrofuran;
at 25 ℃;
for 20h;
Yield given;
DOI:10.1021/jo00031a019
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 10percent aq. HCl / tetrahydrofuran / 1.5 h / 25 °C
2: trimethylsilyl trifluoromethanesulfonate (TMSOTf) / tetrahydrofuran / 20 h / 25 °C
With
hydrogenchloride; trimethylsilyl trifluoromethanesulfonate;
In
tetrahydrofuran;
DOI:10.1021/jo00031a019
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 83 percent / imidazole / dimethylformamide / 16 h / 25 °C
2: 1.) 9-BBN, 2.) 30percent aq. H2O2, 6N aq. NaOH / 1.) THF, 14 h, -80 deg C to r.t., 2.) 2 h, -10 deg C to r.t.
3: 10percent aq. HCl / tetrahydrofuran / 1.5 h / 25 °C
4: trimethylsilyl trifluoromethanesulfonate (TMSOTf) / tetrahydrofuran / 20 h / 25 °C
With
1H-imidazole; hydrogenchloride; sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; trimethylsilyl trifluoromethanesulfonate; dihydrogen peroxide;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jo00031a019
