2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid

Base Information

Chemical Name:2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid
CAS No.:74936-81-5
Molecular Formula:C15H14N2O6
Molecular Weight:318.286
Hs Code.:2933399990
UNII:E8VWY6LL7U
Nikkaji Number:J555.663E
Mol file:74936-81-5.mol

Synonyms:2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid;74936-81-5;E8VWY6LL7U;Lercanidipine Impurity 10;1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid;SCHEMBL3032197;TZDPJNSHSWMCPN-UHFFFAOYSA-N;AKOS025243093;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-

Suppliers and Price of 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid >95%
1g
$ 1771.00

Matrix Scientific
2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid >95%
500mg
$ 1310.00

Total 15 raw suppliers

Chemical Property of 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid

Chemical Property:

Boiling Point:538.9±50.0 °C(Predicted)
PKA:1.38±0.70(Predicted)
PSA：132.45000
Density:1.436±0.06 g/cm3(Predicted)
LogP:2.85080
XLogP3:1.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:318.08518617
Heavy Atom Count:23
Complexity:580

Purity/Quality:

99% ^*data from raw suppliers

2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(C(=C(N1)C)C(=O)O)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)O
Uses 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic Acid is used in the preparation of benidipine hydrochloride metabolites. Benidipine is a highly potent and long-?acting Calcium antagonist now under study as an antihypertensive and as an antianvginal agent.

Technology Process of 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid

There total 2 articles about 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%