4-(4-bromophenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine

Base Information

Chemical Name:4-(4-bromophenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine
CAS No.:75220-83-6
Molecular Formula:C21H17BrN2
Molecular Weight:377.283
Hs Code.:
DSSTox Substance ID:DTXSID40397840

Synonyms:4-(4-bromophenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine;75220-83-6;DTXSID40397840;STK077492;AKOS005391684

Suppliers and Price of 4-(4-bromophenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-(4-bromophenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine

Chemical Property:

PSA：24.39000
LogP:5.70040
XLogP3:5.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:376.05751
Heavy Atom Count:24
Complexity:435

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(NC2=CC=CC=C2N=C1C3=CC=C(C=C3)Br)C4=CC=CC=C4

Technology Process of 4-(4-bromophenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine

There total 5 articles about 4-(4-bromophenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 2403-27-2
1-(4-bromophenyl)-3-phenyl-2-propen-1-one

: 95-54-5
1,2-diamino-benzene

: 75220-83-6
2,3-dihydro-2-phenyl-4-(4-bromophenyl)-1H-1,5-benzodiazepine

Guidance literature:: With N,N'-dimethylbenzylamine; In methanol; for 7h; Heating;
DOI:10.1007/BF00561358

Reference yield: 66.5%

: 72758-69-1,2403-27-2,22966-23-0
(E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one

: 95-54-5
1,2-diamino-benzene

: 1-(2-aminophenyl)-2,6-di(4-bromophenyl)-4-phenyl-1,4-dihydropyridine

: 75220-83-6
2,3-dihydro-2-phenyl-4-(4-bromophenyl)-1H-1,5-benzodiazepine

Guidance literature:: With Bi(NO₃)3 on neutral alumina; at 130 ℃; for 0.433333h; microwave irradiation;
DOI:10.1139/V06-128

Reference yield: 66.0%

: 95-54-5
1,2-diamino-benzene

: 278168-69-7
3-(4-bromophenyl)-1-phenylprop-2-yn-1-ol

: 75220-83-6
2,3-dihydro-2-phenyl-4-(4-bromophenyl)-1H-1,5-benzodiazepine

Guidance literature:: 3-(4-bromophenyl)-1-phenylprop-2-yn-1-ol; With Echavarren's catalyst; In dichloromethane; for 0.166667h;

1,2-diamino-benzene; In dichloromethane; at 60 ℃; for 24h;
DOI:10.1021/acs.orglett.6b01720