2,3-DIHYDRO-2,2-DIMETHYL BENZOFURAN-3,7-DIOL

Base Information

• Chemical Name: 2,3-DIHYDRO-2,2-DIMETHYL BENZOFURAN-3,7-DIOL
• CAS No.: 17781-15-6
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.203
• Mol file: 17781-15-6.mol

Synonyms:2,2-Dimethyl-3,7-dihydroxy-2,3-dihydrobenzofuran;2,3-Dihydro-2,2-dimethyl-3,7-benzofurandiol; 2,3-Dihydro-2,2-dimethyl-3,7-dihydroxybenzofuran;2,3-Dihydro-3,7-dihydroxy-2,2-dimethylbenzofuran;3,7-Dihydroxy-2,2-dimethyl-2,3-dihydrobenzofuran

Chemical Property of 2,3-DIHYDRO-2,2-DIMETHYL BENZOFURAN-3,7-DIOL

Chemical Property:

• Vapor Pressure: 0.000837mmHg at 25°C
• Boiling Point: 292.4°Cat760mmHg
• PKA: 9.90±0.60(Predicted)
• Flash Point: 130.7°C
• PSA: 49.69000
• Density: 1.256g/cm³
• LogP: 1.59660
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,2-Dimethyl-2,3-dihydrobenzofuran-3,7-diol is a phenolic metabolite of carbofuran; carbofuran (C176590) is a carbamate pesticide.

Technology Process of 2,3-DIHYDRO-2,2-DIMETHYL BENZOFURAN-3,7-DIOL

There total 2 articles about 2,3-DIHYDRO-2,2-DIMETHYL BENZOFURAN-3,7-DIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbosulfan (55285-14-8) → 3-Hydroxycarbofuran (16655-82-6) + 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate (1563-66-2) + 2,3-dihydro-3-oxo-2,2-dimethylbenzofuran-7-ol (17781-16-7) + 2,3-dihydro-3-oxo-2,2-dimethylbenzofuran-7-yl methylcarbamate (16709-30-1) + C20H32N2O4S (1260117-81-4) + dibutylamine (111-92-2) + 2,3-dihydro-3-hydroxy-2,2-dimethylbenzofuran-7-ol (17781-15-6)

Guidance literature:

With liver microsomal protein; NADPH; In dimethyl sulfoxide; at 37 ℃; pH=7.4; Reagent/catalyst; Kinetics; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1016/j.cbi.2010.03.024

Reference yield:

2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate (1563-66-2) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 2,3-dihydro-3-oxo-2,2-dimethylbenzofuran-7-ol (17781-16-7) + 2,3-dihydro-2,2-dimethylbenzofuran-7-yl formate + 2,3-dihydro-3-hydroxy-2,2-dimethylbenzofuran-7-ol (17781-15-6)

Guidance literature:

With dihydrogen peroxide; iron; sodium chloride; In water; at 25 ℃; Further Variations:; Temperatures; Activation energy; Product distribution; Electrolysis;

DOI:10.1021/jf034311f

upstream raw materials:

2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate

carbosulfan

Refernces

• 1、 Wang, Qiquan,Lemley, Ann T.. "Competitive degradation and detoxification of carbamate insecticides by membrane anodic fenton treatment". . p. 5382 - 5390. Retrieved 2007/10/03.