1-Bromo-1-chloro-1,2,2,2-tetrafluoroethane

Base Information

• Chemical Name: 1-Bromo-1-chloro-1,2,2,2-tetrafluoroethane
• CAS No.: 754-20-1
• Molecular Formula: C2BrClF4
• Molecular Weight: 215.373
• DSSTox Substance ID: DTXSID60536931
• Nikkaji Number: J632.921G
• Mol file: 754-20-1.mol

Synonyms:1-Bromo-1-chloro-1,2,2,2-tetrafluoroethane;754-20-1;SCHEMBL9247452;DTXSID60536931;KKDVQRXZVBSJCF-UHFFFAOYSA-N

Chemical Property of 1-Bromo-1-chloro-1,2,2,2-tetrafluoroethane

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 213.88080
• Heavy Atom Count: 8
• Complexity: 90.5

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(C(F)(Cl)Br)(F)(F)F

Technology Process of 1-Bromo-1-chloro-1,2,2,2-tetrafluoroethane

There total 5 articles about 1-Bromo-1-chloro-1,2,2,2-tetrafluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.3%

1,2-dibromo-1,1,2,2-tetrafluoroethane (124-73-2) → 1-bromo-1-chloro-1,2,2,2-tetrafluoro-ethane (754-20-1) + 1,1,1-tribromotrifluoroethane (354-48-3) + 1-chloro-1,1-dibromotrifluoroethane (754-17-6) + 1,1-dibromo-1,2,2,2-tetrafluoroethane (27336-23-8)

Guidance literature:

With aluminium trichloride; at 50 - 55 ℃; for 22h; Further byproducts given;

DOI:10.1016/S0022-1139(00)80974-4

Reference yield: 28.0%

Chlorotrifluoroethylene (79-38-9,9036-80-0) + C3BrClF6O (152239-97-9) → Carbonyl fluoride (353-50-4) + 1-bromo-1-chloro-1,2,2,2-tetrafluoro-ethane (754-20-1) + 2-Bromo-1-(1,2-dichloro-1,2,2-trifluoro-ethoxy)-1,1,2,3,3,3-hexafluoro-propane

Guidance literature:

In trichlorofluoromethane; for 19h; -141 degC to 22 degC;

DOI:10.1016/S0022-1139(00)80070-6

Reference yield: 14.5%

1,2-dibromo-1,1,2,2-tetrafluoroethane (124-73-2) → bromopentafluoroethane (354-55-2) + 1-bromo-1-chloro-1,2,2,2-tetrafluoro-ethane (754-20-1) + 1,1,1-tribromotrifluoroethane (354-48-3) + 1,1-dibromo-1,2,2,2-tetrafluoroethane (27336-23-8)

Guidance literature:

With aluminium trichloride; at 50 - 55 ℃; for 22h; Further byproducts given;

DOI:10.1016/S0022-1139(00)80974-4

upstream raw materials:

Vinylidene fluoride

C₃BrClF₆O

1,2-dibromo-1,1,2,2-tetrafluoroethane

Chlorotrifluoroethylene

Downstream raw materials:

2,3,3,3-tetrafluoropropionic acid

2-chloro-2,3,3,3-tetrafluoro-propanoic acid