2-Propanone, 1,3-diphenyl-, O,O'-methylenedioxime

Base Information

• Chemical Name: 2-Propanone, 1,3-diphenyl-, O,O'-methylenedioxime
• CAS No.: 75498-70-3
• Molecular Formula: C31H30N2O2
• Molecular Weight: 462.591
• Mol file: 75498-70-3.mol

Synonyms:

Chemical Property of 2-Propanone, 1,3-diphenyl-, O,O'-methylenedioxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propanone, 1,3-diphenyl-, O,O'-methylenedioxime

There total 3 articles about 2-Propanone, 1,3-diphenyl-, O,O'-methylenedioxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

dichloromethane (75-09-2) + 1,3-diphenylpropan-2-one oxime (1788-31-4) → 1,3-Diphenyl-propan-2-one O-(1-benzyl-2-phenyl-ethylideneaminooxymethyl)-oxime (75498-70-3)

Guidance literature:

With potassium tert-butylate; 18-crown-6 ether;

DOI:10.1016/S0040-4039(00)71386-4

Reference yield: 24.0%

dichloromethane (75-09-2) + 1,3-diphenylpropan-2-one oxime (1788-31-4) → 1,3-Diphenyl-propan-2-one O-(1-benzyl-2-phenyl-ethylideneaminooxymethyl)-oxime (75498-70-3)

Guidance literature:

With (2-methylallyl)palladium-chloride dimer; for 72h; Product distribution; Mechanism; Ambient temperature;

DOI:10.1246/bcsj.58.194

Reference yield: 15.0%

(2-methylallyl)palladium-chloride dimer + 1,3-diphenylpropan-2-one oxime (1788-31-4) → [(dibenzyl ketone oximato)2(dibenzyl ketone oxime)2]Pd + 1,3-Diphenyl-propan-2-one O-(1-benzyl-2-phenyl-ethylideneaminooxymethyl)-oxime (75498-70-3)

Guidance literature:

With dichloromethane; In dichloromethane; byproducts: potassium chloride; KO2, Pd complex and ketoxime stirred in CH2Cl2 soln. for 72 h at room temp. under Ar; KCl filtered off, concd. in vac., chromd. (Al2O3, hexane-EtOAc, EtOAc, CH2Cl2), recrystd. from CH2Cl2-EtOAc; elem. anal.;

DOI:10.1246/bcsj.58.194

upstream raw materials:

dichloromethane

1,3-diphenylpropan-2-one oxime