Cyclohexanamine, 4-[4-(cyclopropylmethyl)-1-piperazinyl]-, cis-

Base Information

Chemical Name:Cyclohexanamine, 4-[4-(cyclopropylmethyl)-1-piperazinyl]-, cis-
CAS No.:755039-90-8
Molecular Formula:C14H27N3
Molecular Weight:237.388
Hs Code.:
Mol file:755039-90-8.mol

Synonyms:cis-4-(4-cyclopropylmethyl-piperazin-1-yl)-cyclohexylamine;(cis)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexanamine;2-(3,4-dihydro-2H-1-benzopyran-4-yl)acetic acid;(3,4-dihydro-1(2H)-benzopyran-4-yl)ethanoic acid;(chroman-4-yl)acetic acid;2H-1-Benzopyran-4-acetic acid,3,4-dihydro;2-(chroman-4-yl)acetic acid;

Suppliers and Price of Cyclohexanamine, 4-[4-(cyclopropylmethyl)-1-piperazinyl]-, cis-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of Cyclohexanamine, 4-[4-(cyclopropylmethyl)-1-piperazinyl]-, cis-

Chemical Property:

Vapor Pressure:0.00022mmHg at 25°C
Boiling Point:326.1oC at 760 mmHg
PKA:10.54±0.70(Predicted)
Flash Point:148.9oC
PSA：32.50000
Density:1.063g/cm3
LogP:1.86000

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclohexanamine, 4-[4-(cyclopropylmethyl)-1-piperazinyl]-, cis-

There total 9 articles about Cyclohexanamine, 4-[4-(cyclopropylmethyl)-1-piperazinyl]-, cis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 755039-88-4
(cis)-N,N-dibenzyl-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexanamine

: 755039-90-8
(cis)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexanamine

Guidance literature:: With hydrogen; acetic acid; palladium 10% on activated carbon; In methanol; dichloromethane; at 20 - 30 ℃; for 12h; under 2280.15 Torr; Inert atmosphere;

Reference yield: 61.0%

: 57184-25-5
1-cyclopropylmethylpiperazine

: 149506-79-6
4-(dibenzylamino)cyclohexanone

: 876461-31-3
(trans)-4-(4-(cyclopropylmethyl)piperazin-1-yl)cyclohexanamine

: 755039-90-8
(cis)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexanamine

Guidance literature:: With sodium tris(acetoxy)borohydride; potassium carbonate; In dichloromethane; at 20 ℃; for 12h;

Reference yield:

: 149506-79-6
4-(dibenzylamino)cyclohexanone

: 755039-90-8
(cis)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexanamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium acetate; sodium tris(acetoxy)borohydride / acetonitrile / 12 h / 20 - 30 °C / pH 6 - 7 / Inert atmosphere

1.2: pH 8

2.1: hydrogen; acetic acid / palladium 10% on activated carbon / dichloromethane; methanol / 12 h / 20 - 30 °C / 2280.15 Torr / Inert atmosphere

With hydrogen; sodium acetate; sodium tris(acetoxy)borohydride; acetic acid; palladium 10% on activated carbon; In methanol; dichloromethane; acetonitrile;