7a-Methyl-5,7a-dihydro-1H-inden-1-one

Base Information

• Chemical Name: 7a-Methyl-5,7a-dihydro-1H-inden-1-one
• CAS No.: 75950-74-2
• Molecular Formula: C10H10O
• Molecular Weight: 146.189
• DSSTox Substance ID: DTXSID50505252
• Mol file: 75950-74-2.mol

Synonyms:75950-74-2;7a-Methyl-5,7a-dihydro-1H-inden-1-one;DTXSID50505252

Chemical Property of 7a-Methyl-5,7a-dihydro-1H-inden-1-one

Chemical Property:

• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 146.073164938
• Heavy Atom Count: 11
• Complexity: 294

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12C=CCC=C1C=CC2=O

Technology Process of 7a-Methyl-5,7a-dihydro-1H-inden-1-one

There total 1 articles about 7a-Methyl-5,7a-dihydro-1H-inden-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7a-Methyl-2-phenylselanyl-2,3,5,7a-tetrahydro-inden-1-one (75950-73-1) → (E)-3-(2-methylphenyl)acrylic acid (939-57-1,2373-76-4,41397-71-1) + 5,7a-dihydro-7a-methyl-1H-inden-1-one (75950-74-2)

Guidance literature:

With dihydrogen peroxide; In tetrahydrofuran; pyridine; at 5 - 10 ℃; Yields of byproduct given;

Reference yield:

Methyl fluorosulfonate (421-20-5) + 5,7a-dihydro-7a-methyl-1H-inden-1-one (75950-74-2) → 3-(2'-methylphenyl)-(Z)-propenoic acid methyl ester (75950-75-3) + 3-methoxy-3a-methyl-3aH-indene (76051-89-3)

Guidance literature:

With 18-crown-6 ether; potassium hydride; Yield given. Multistep reaction; 1) ether, -18 deg C, 30 min; 2) 5 min;

DOI:10.1039/P19810003214

upstream raw materials:

7a-Methyl-2-phenylselanyl-2,3,5,7a-tetrahydro-inden-1-one

Downstream raw materials:

3-(2'-methylphenyl)-(Z)-propenoic acid methyl ester

3-methoxy-3a-methyl-3aH-indene