(2,3-Dihydro-1H-inden-2-YL)methanol

Base Information

• Chemical Name: (2,3-Dihydro-1H-inden-2-YL)methanol
• CAS No.: 5445-45-4
• Molecular Formula: C10H12 O
• Molecular Weight: 148.205
• Hs Code.: 2906299090
• European Community (EC) Number: 834-268-2
• NSC Number: 22042
• UNII: 425V2UFV9L
• DSSTox Substance ID: DTXSID40281573
• Nikkaji Number: J2.422.435J
• Wikidata: Q82015569
• Mol file: 5445-45-4.mol

Synonyms:5445-45-4;(2,3-DIHYDRO-1H-INDEN-2-YL)METHANOL;2,3-dihydro-1H-inden-2-ylmethanol;2-hydroxymethylindane;2-Indanmethanol;indan-2-ylmethanol;1H-Indene-2-methanol, 2,3-dihydro-;(Indan-2-yl)methanol;NSC-22042;425V2UFV9L;MFCD08235017;2,3-DIHYDRO-1H-INDENE-2-METHANOL;NSC22042;2-hydroxymethyl-indan;UNII-425V2UFV9L;SCHEMBL835059;DTXSID40281573;ULVJTHHSGWAIOA-UHFFFAOYSA-N;CS-B1058;AKOS005216196;MB05939;AS-42045;FT-0777942;EN300-182222;A870442;J-500555;Z1198176601

Chemical Property of (2,3-Dihydro-1H-inden-2-YL)methanol

Chemical Property:

• Vapor Pressure: 2.12E-14mmHg at 25°C
• Boiling Point: 263.7°Cat760mmHg
• Flash Point: 122.4°C
• PSA: 20.23000
• Density: 1.08g/cm³
• LogP: 1.39370
• Storage Temp.: 2-8°C
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 148.088815002
• Heavy Atom Count: 11
• Complexity: 119

Purity/Quality:

97% ^*data from raw suppliers

(2,3-dihydro-1h-inden-2-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(CC2=CC=CC=C21)CO

Technology Process of (2,3-Dihydro-1H-inden-2-YL)methanol

There total 13 articles about (2,3-Dihydro-1H-inden-2-YL)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-indancarboxylic acid (25177-85-9) → 2-(hydroxymethyl)indan (5445-45-4)

Guidance literature:

With lithium aluminium hydride; In tetrahydrofuran; at 0 ℃; for 2h;

Reference yield: 89.0%

indene-2-carboxylic acid (41712-14-5) → 2-(hydroxymethyl)indan (5445-45-4)

Guidance literature:

With dimethylsulfide borane complex; In tetrahydrofuran; Heating;

DOI:10.1002/hlca.200390086

Reference yield: 76.0%

2-methylene-2,3-dihydro-1H-indene (68846-65-1) + 9-bora-bicyclo[3.3.1]nonane (280-64-8) → cis-1,5-cyclooctanediol + 2-(hydroxymethyl)indan (5445-45-4)

Guidance literature:

2-methylene-2,3-dihydro-1H-indene; 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; at 20 ℃; for 12h;

With sodium hydroxide; dihydrogen peroxide; at 50 ℃; for 2h;

DOI:10.1055/s-2006-958950

upstream raw materials:

indan-2-carboxylic acid ethyl ester

2,6-dimethyl-4-heptanol

toluene

(4ar,9bt)-4,4a,5,9b-tetrahydro-indeno[1,2-d][1,3]dioxin

Downstream raw materials:

2-indanemethanol methanesulfonate

1-(2,3-dihydro-1H-inden-2-yl)-2-oxo-2-phenylethyl 4-methylbenzene-1-sulfonate

2-hydroxy-2-(indan-2-yl)-1-phenylethan-1-one

2‐(bromomethyl)‐2,3‐dihydro‐1H‐indene