41712-14-5Relevant articles and documents
Hydrogen-Bonding Amidoindoles in the Presence of Anions: An X-ray Structure of a Receptor at the Acid–Base Half-Equivalence that Binds an Anion
Koeller, Sylvain,Lescure, Marie-Hélène,Davies, Clotilde,Desvergne, Jean-Pierre,Massip, Stéphane,Bibal, Brigitte
, p. 5627 - 5631 (2017)
Hydrogen-bonding catalysts based on (thio)amidoindole moieties were evaluated in the presence of anions as potent anion receptors and/or acidic partners involved in acid–base reactions. In particular, we focused on their behavior at the acid–base half-equivalence point in the presence of basic anions such as fluoride and benzoate salts. Among three isolated X-ray structures, an amidoindole in the presence of fluoride and hexafluorophosphate salts formed, at the acid–base half-equivalence point, an unprecedented sandwich complex between two receptors and a PF6– anion.
Method for preparing alpha, beta-unsaturated carboxylic acid by reacting alkenyl boron compound with carbon dioxide under catalysis of cuprous halide
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Paragraph 0059-0060, (2020/06/17)
The invention discloses a method for preparing alpha, beta-unsaturated carboxylic acid through a carboxylation reaction of an alkenyl boron compound and carbon dioxide under the catalysis of cuprous halide. According to the method, carbon dioxide is used as a C1 source, the cuprous halide is adopted for catalysis, and alkoxide serves as alkali to react in an organic solvent, so the method is simple and easy to implement, has a wide substrate application range, converts various alkenyl boron compounds such as alkenyl boric acid, alkenyl borate and borate into corresponding alpha, beta-unsaturated carboxylic acid under mild conditions, and has a very high yield. The obtained product alpha, beta-unsaturated carboxylic acid is an important intermediate for preparing fine chemical products suchas perfumes, insecticides and the like.
Cyclopentadienyl molybdenum(II) compounds bearing carboxylic acid functional group
Schejbal, Ji?í,Melounková, Lucie,Vinklárek, Jaromír,?ezá?ová, Martina,R??i?ková, Zdeňka,Císa?ová, Ivana,Honzí?ek, Jan
, p. 66 - 73 (2018/05/09)
This work describes a procedure giving cyclopentadienyl molybdenum(II) compounds bearing carboxylic acid function group. It involves synthesis of carboxylic acid ester functionalized cyclopentadienides, their coordination to molybdenum(II) precursor and saponification of ester function groups. The method is not limited only to compounds with the function group directly attached in the cyclopentadienyl ring but also to those functionalized in the side chain. The attempts to synthesize the indenyl analogues were only partially successful due to low stability in the saponification step. All reported structure types were elucidated from spectroscopic measurements and verified by X-ray crystallography. The second part of the work describes an effect of the outer-coordination sphere on cytotoxicity of the cationic molybdenum(II) compounds bearing N,N-chelating ligands. The cytotoxicity of the modified species bearing phenanthroline ligand toward human leukemia cells MOLT-4 (IC50 = 10.5 ± 0.5 μmol l?1) is higher than reported for cisplatin (IC50 = 15.8 ± 1.9 μmol l?1).
