2,4-Difluoro-3-methylaniline

Base Information

Chemical Name:2,4-Difluoro-3-methylaniline
CAS No.:76350-70-4
Molecular Formula:C7H7F2N
Molecular Weight:143.13400
Hs Code.:2921420090
DSSTox Substance ID:DTXSID60510110
Wikidata:Q72463373
Mol file:76350-70-4.mol

Synonyms:2,4-DIFLUORO-3-METHYLANILINE;76350-70-4;2,4-Difluoro-m-toluidine;SCHEMBL2284180;DTXSID60510110;GEMLIOXWQRDDOA-UHFFFAOYSA-N;AMY36973;MFCD09261073;AKOS006332193;2 pound not4-Difluoro-3-methylaniline;DS-6868;SY011108;C76442;EN300-175773;A865496

Suppliers and Price of 2,4-Difluoro-3-methylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2,4-Difluoro-3-methylaniline 96%
10g
$ 743.00

Crysdot
2,4-Difluoro-3-methylaniline 96%
5g
$ 446.00

Chemenu
2,4-Difluoro-3-methylaniline 95+%
5g
$ 421.00

Chemenu
2,4-Difluoro-3-methylaniline 95+%
1g
$ 153.00

Chemenu
2,4-Difluoro-3-methylaniline 95+%
10g
$ 701.00

American Custom Chemicals Corporation
2,4-DIFLUORO-3-METHYLANILINE 95.00%
5MG
$ 499.53

Ambeed
2,4-Difluoro-3-methylaniline 96%
1g
$ 90.00

Alichem
2,4-Difluoro-3-methylaniline
5g
$ 450.00

Alichem
2,4-Difluoro-3-methylaniline
10g
$ 750.00

Alichem
2,4-Difluoro-3-methylaniline
1g
$ 159.00

Total 13 raw suppliers

Chemical Property of 2,4-Difluoro-3-methylaniline

Chemical Property:

Boiling Point:189℃
PKA:3.39±0.10(Predicted)
Flash Point:79℃
PSA：26.02000
Density:1.229
LogP:2.43660
Storage Temp.:2-8°C(protect from light)
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:143.05465555
Heavy Atom Count:10
Complexity:118

Purity/Quality:

97% ^*data from raw suppliers

2,4-Difluoro-3-methylaniline 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1F)N)F

Technology Process of 2,4-Difluoro-3-methylaniline

There total 3 articles about 2,4-Difluoro-3-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: tin(II)chloride dihydrate

: 79562-49-5
2,4-difluoro-3-methyl-nitrobenzene

: 76350-70-4
2,4-difluoro-3-methyl-aniline

Guidance literature:: In hydrogenchloride; water;

Reference yield: 85.0%

: 79562-49-5
2,4-difluoro-3-methyl-nitrobenzene

: 76350-70-4
2,4-difluoro-3-methyl-aniline

Guidance literature:: With hydrogenchloride; tin(ll) chloride; In methanol; for 3h; Ambient temperature;
DOI:10.1248/cpb.30.3530

Reference yield:

: 443-84-5
2,6-difluorotoluene

: 76350-70-4
2,4-difluoro-3-methyl-aniline

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / fuming HNO₃, conc. H₂SO₄ / 1.5 h / 20 - 25 °C

2: 85 percent / SnCl₂*2H₂O, conc. HCl / methanol / 3 h / Ambient temperature

With hydrogenchloride; sulfuric acid; nitric acid; tin(ll) chloride; In methanol;
DOI:10.1248/cpb.30.3530