Silane, (1,1-dimethylethyl)[[2-(1,3-dithian-2-yl)-4,5-dimethoxyphenyl]thio]dimeth yl-

Base Information

• Chemical Name: Silane, (1,1-dimethylethyl)[[2-(1,3-dithian-2-yl)-4,5-dimethoxyphenyl]thio]dimeth yl-
• CAS No.: 765292-79-3
• Molecular Formula: C18H30O2S3Si
• Molecular Weight: 402.719
• Mol file: 765292-79-3.mol

Synonyms:

Chemical Property of Silane, (1,1-dimethylethyl)[[2-(1,3-dithian-2-yl)-4,5-dimethoxyphenyl]thio]dimeth yl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Silane, (1,1-dimethylethyl)[[2-(1,3-dithian-2-yl)-4,5-dimethoxyphenyl]thio]dimeth yl-

There total 3 articles about Silane, (1,1-dimethylethyl)[[2-(1,3-dithian-2-yl)-4,5-dimethoxyphenyl]thio]dimeth yl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4',5'-dimethoxy-2'-aminophenyl)-1,3-dithiane (765292-77-1) → 2'-[4',5'-dimethoxy-2'-(tert-butyldimethylsilylsulfanyl)phenyl]-1,3-dithiane (765292-79-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: aq. HCl; sodium nitrite / H₂O / 0.5 h / 0 - 5 °C

1.2: potassium ethyl xanthate / H₂O / 0.83 h / 40 - 45 °C

1.3: 72 percent / LiAlH₄ / tetrahydrofuran / 2 h

2.1: 77 percent / pyridine / CH₂Cl₂ / 20 °C

With pyridine; hydrogenchloride; sodium nitrite; In dichloromethane; water;

DOI:10.1021/jo049344o

Reference yield:

2-(4',5'-dimethoxy-2'-nitrophenyl)-1,3-dithiane (765293-06-9) → 2'-[4',5'-dimethoxy-2'-(tert-butyldimethylsilylsulfanyl)phenyl]-1,3-dithiane (765292-79-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 81 percent / iron; ammonium chloride / H₂O; ethanol / 3.5 h / Heating

2.1: aq. HCl; sodium nitrite / H₂O / 0.5 h / 0 - 5 °C

2.2: potassium ethyl xanthate / H₂O / 0.83 h / 40 - 45 °C

2.3: 72 percent / LiAlH₄ / tetrahydrofuran / 2 h

3.1: 77 percent / pyridine / CH₂Cl₂ / 20 °C

With pyridine; hydrogenchloride; ammonium chloride; iron; sodium nitrite; In ethanol; dichloromethane; water;

DOI:10.1021/jo049344o

Reference yield:

6-nitroveratraldehyde (20357-25-9) → 2'-[4',5'-dimethoxy-2'-(tert-butyldimethylsilylsulfanyl)phenyl]-1,3-dithiane (765292-79-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 78 percent / boron trifluoride etherate; acetic acid / toluene

2.1: 81 percent / iron; ammonium chloride / H₂O; ethanol / 3.5 h / Heating

3.1: aq. HCl; sodium nitrite / H₂O / 0.5 h / 0 - 5 °C

3.2: potassium ethyl xanthate / H₂O / 0.83 h / 40 - 45 °C

3.3: 72 percent / LiAlH₄ / tetrahydrofuran / 2 h

4.1: 77 percent / pyridine / CH₂Cl₂ / 20 °C

With pyridine; hydrogenchloride; boron trifluoride diethyl etherate; ammonium chloride; iron; acetic acid; sodium nitrite; In ethanol; dichloromethane; water; toluene;

DOI:10.1021/jo049344o

upstream raw materials:

2-(4',5'-dimethoxy-2'-aminophenyl)-1,3-dithiane

2-(4',5'-dimethoxy-2'-nitrophenyl)-1,3-dithiane

6-nitroveratraldehyde

Downstream raw materials:

5,6-dimethoxy-2-(4'-methoxyphenyl)-benzo[b]thiophene