2-Butylpyrazolo[1,5-a]pyridine

Base Information

Chemical Name:2-Butylpyrazolo[1,5-a]pyridine
CAS No.:76943-48-1
Molecular Formula:C₁₁H₁₄N₂
Molecular Weight:174.246
Hs Code.:
DSSTox Substance ID:DTXSID70506307
Wikidata:Q82362003

Synonyms:2-butylpyrazolo[1,5-a]pyridine;76943-48-1;DTXSID70506307;2-butyl-8H-pyrazolo[1,5-a]pyridine

Suppliers and Price of 2-Butylpyrazolo[1,5-a]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
2-butyl-Pyrazolo[1,5-a]pyridine 97.00%
5G
$ 3900.00

Total 0 raw suppliers

Chemical Property of 2-Butylpyrazolo[1,5-a]pyridine

Chemical Property:

PSA：17.30000
Density:1.04±0.1 g/cm3(Predicted)
LogP:2.67690
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:174.115698455
Heavy Atom Count:13
Complexity:158

Purity/Quality:: 2-butyl-Pyrazolo[1,5-a]pyridine 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC1=NN2C=CC=CC2=C1

Technology Process of 2-Butylpyrazolo[1,5-a]pyridine

There total 4 articles about 2-Butylpyrazolo[1,5-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 76943-46-9
2,4,6-Trimethyl-benzenesulfonate1-amino-2-hex-1-ynyl-pyridinium;

: 76943-48-1
2-butylpyrazolo[1,5-a]pyridine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; Ambient temperature;
DOI:10.1039/c39800001109

Reference yield: 55.0%

: 23031-08-5
benzoyl(pyridin-1-ium-1-yl)amide

: 693-02-7
hex-1-yne

: 76943-48-1
2-butylpyrazolo[1,5-a]pyridine

Guidance literature:: With palladium bromide; P(p-CH₃OC₆H₄)3; silver benzoate; In 1,4-dioxane; at 125 ℃; for 16h; Inert atmosphere;
DOI:10.1021/jo201303x

Reference yield:

: 110-86-1
pyridine

: 76943-48-1
2-butylpyrazolo[1,5-a]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: O-(2,4-dinitrophenyl)hydroxylamine / acetonitrile / 24 h / 40 °C / Inert atmosphere

2.1: sodium hydroxide / tetrahydrofuran; water / 0.08 h / 20 °C / Inert atmosphere

2.2: 5 h / Inert atmosphere

3.1: palladium bromide; P(p-CH₃OC₆H₄)3; silver benzoate / 1,4-dioxane / 16 h / 125 °C / Inert atmosphere

With palladium bromide; P(p-CH₃OC₆H₄)3; silver benzoate; O-(2,4-dinitrophenyl)hydroxylamine; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; water; acetonitrile;
DOI:10.1021/jo201303x