5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one

Base Information

Chemical Name:5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one
CAS No.:77398-90-4
Molecular Formula:C15H22O4
Molecular Weight:266.337
Hs Code.:
DSSTox Substance ID:DTXSID70415723
Wikidata:Q82224703
ChEMBL ID:CHEMBL3883439

Synonyms:4-Gingerol;5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one;CHEMBL3883439;77398-90-4;3-Octanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-;SCHEMBL20668437;DTXSID70415723;CHEBI:156171;GDRKZARFCIYVCI-UHFFFAOYSA-N;BDBM50210051

Suppliers and Price of 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:266.15180918
Heavy Atom Count:19
Complexity:267

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC(CC(=O)CCC1=CC(=C(C=C1)O)OC)O

Technology Process of 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one

There total 15 articles about 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 91815-19-9
4-{2-[2-(2-Hydroxy-pentyl)-[1,3]dioxolan-2-yl]-ethyl}-2-methoxy-phenol

: 77398-90-4
5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one

Guidance literature:: With hydrogen fluoride; In water; acetonitrile; for 0.5h; Ambient temperature;

Reference yield: 45.0%

: 77333-99-4
(E)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)oct-1-en-3-one

: 77398-90-4
5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 2h;
DOI:10.1021/acs.jmedchem.0c00630

Reference yield: 13.0%

: 122-48-5
4-(4-hydroxy-3-methoxyphenyl)-2-butanone

: 123-72-8
butyraldehyde

: 77398-90-4
5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one

Guidance literature:: 4-(4-hydroxy-3-methoxyphenyl)-2-butanone; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 1h;

butyraldehyde; In tetrahydrofuran; at -78 ℃; for 3h; Time;
DOI:10.1021/acs.jmedchem.7b01426