5-Bromo-2-chlorophenylboronic acid

Base Information

• Chemical Name: 5-Bromo-2-chlorophenylboronic acid
• CAS No.: 774608-50-3
• Molecular Formula: C6H5BBrClO2
• Molecular Weight: 235.272
• Hs Code.: 2931900090
• Mol file: 774608-50-3.mol

Synonyms:Benzenamine,5-bromo-2-chloro-,hydrochloride;5-bromo-2-chloro-phenylboronic acid;5-bromo-2-chloro-phenylamine hydrochloride;5-bromo-2-chloroaniline hydrochloride;

Chemical Property of 5-Bromo-2-chlorophenylboronic acid

Chemical Property:

• PSA: 40.46000
• LogP: 0.78230

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2-chlorophenylboronicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Bromo-2-chlorophenylboronic acid

There total 3 articles about 5-Bromo-2-chlorophenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-1-chloro-2-iodobenzene (774608-49-0) + Trimethyl borate (121-43-7,63156-11-6) → 5-bromo-2-chloro-phenylboronic acid (774608-50-3)

Guidance literature:

4-bromo-1-chloro-2-iodobenzene; With isopropylmagnesium chloride; In tetrahydrofuran; at -75 - 20 ℃; for 2h;

Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃; for 2h;

With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃;

Reference yield:

C8H9BBrClO2 → 5-bromo-2-chloro-phenylboronic acid (774608-50-3)

Guidance literature:

With hydrogenchloride; water; In tetrahydrofuran;

Reference yield:

4-bromo-2-iodoaniline (66416-72-6) → 5-bromo-2-chloro-phenylboronic acid (774608-50-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tert.-butylnitrite; copper dichloride / acetonitrile / 3 h / 60 °C

1.2: 20 °C

2.1: isopropylmagnesium chloride / tetrahydrofuran / 2 h / -75 - 20 °C

2.2: 2 h / -78 - 20 °C

2.3: 20 °C

With tert.-butylnitrite; isopropylmagnesium chloride; copper dichloride; In tetrahydrofuran; acetonitrile;

upstream raw materials:

4-bromo-1-chloro-2-iodobenzene

Trimethyl borate

4-bromo-2-iodoaniline

Downstream raw materials:

5-bromo-2-chlorophenyllead triacetate

C₁₄H₁₂BrClO₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 774608-50-3 5-Bromo-2-chlorophenylboronic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send