1-(6-Nitropyridin-3-yl)piperazine

Base Information

Chemical Name:1-(6-Nitropyridin-3-yl)piperazine
CAS No.:775288-71-6
Molecular Formula:C9H12N4O2
Molecular Weight:208.22
Hs Code.:2933990090
European Community (EC) Number:836-264-6
DSSTox Substance ID:DTXSID80457598
Wikidata:Q82280495
Mol file:775288-71-6.mol

Synonyms:1-(6-nitropyridin-3-yl)piperazine;775288-71-6;1-(6-Nitro-3-pyridyl)piperazine;MFCD09041112;Piperazine, 1-(6-nitro-3-pyridinyl)-;SCHEMBL1392957;SCHEMBL17525876;AMY5311;DTXSID80457598;UBCDLQPOKISIDX-UHFFFAOYSA-N;CS-B0330;AKOS000123471;1-(6-Nitro-pyridin-3-yl)-piperazine;AB91080;Piperazine,1-(6-nitro-3-pyridinyl)-;AC-31710;DS-17738;SY061053;EN300-35856;F11579;A865209;A1-02677;Z330909656

Suppliers and Price of 1-(6-Nitropyridin-3-yl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-?(6-?Nitro-?3-?pyridinyl)?piperazine
100mg
$ 105.00

Crysdot
1-(6-Nitropyridin-3-yl)piperazine 95+%
1g
$ 221.00

ChemScene
1-(6-Nitropyridin-3-yl)piperazine 99.60%
1g
$ 92.00

ChemScene
1-(6-Nitropyridin-3-yl)piperazine 99.60%
10g
$ 680.00

Chemenu
1-(6-nitropyridin-3-yl)piperazine 95%
1g
$ 281.00

American Custom Chemicals Corporation
1-(6-NITROPYRIDIN-3-YL)PIPERAZINE 95.00%
5G
$ 1928.08

American Custom Chemicals Corporation
1-(6-NITROPYRIDIN-3-YL)PIPERAZINE 95.00%
2.5G
$ 1473.14

American Custom Chemicals Corporation
1-(6-NITROPYRIDIN-3-YL)PIPERAZINE 95.00%
1G
$ 983.52

Ambeed
1-(6-Nitropyridin-3-yl)piperazine 95+%
1g
$ 65.00

Ambeed
1-(6-Nitropyridin-3-yl)piperazine 95+%
100mg
$ 15.00

Total 35 raw suppliers

Chemical Property of 1-(6-Nitropyridin-3-yl)piperazine

Chemical Property:

Vapor Pressure:2.34E-07mmHg at 25°C
Boiling Point:422.8oC at 760 mmHg
PKA:8.50±0.10(Predicted)
Flash Point:209.5oC
PSA：73.98000
Density:1.278g/cm3
LogP:1.31640
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Solubility.:Chloroform; Methanol
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:208.09602564
Heavy Atom Count:15
Complexity:225

Purity/Quality:

99%, ^*data from raw suppliers

1-?(6-?Nitro-?3-?pyridinyl)?piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C2=CN=C(C=C2)[N+](=O)[O-]
Uses 1-?(6-?Nitro-?3-?pyridinyl)?piperazine is a reagent used in the preparation of highly potent and orally bioavailable 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amine cyclin-dependant kinases as anticancer agents. Also is an impurity of Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.

Technology Process of 1-(6-Nitropyridin-3-yl)piperazine

There total 5 articles about 1-(6-Nitropyridin-3-yl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%