5-Bromo-2-nitropyridine

Base Information

Chemical Name:5-Bromo-2-nitropyridine
CAS No.:39856-50-3
Molecular Formula:C5H3BrN2O2
Molecular Weight:202.995
Hs Code.:29339900
European Community (EC) Number:609-748-8
DSSTox Substance ID:DTXSID20355827
Nikkaji Number:J1.215.692H
Wikidata:Q72448708
Mol file:39856-50-3.mol

Synonyms:5-bromo-2-nitropyridine

Suppliers and Price of 5-Bromo-2-nitropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-2-nitropyridine
1g
$ 45.00

TCI Chemical
5-Bromo-2-nitropyridine >98.0%(GC)
5g
$ 72.00

TCI Chemical
5-Bromo-2-nitropyridine >98.0%(GC)
1g
$ 25.00

SynQuest Laboratories
5-Bromo-2-nitropyridine
25 g
$ 53.00

SynQuest Laboratories
5-Bromo-2-nitropyridine
5 g
$ 16.00

Sigma-Aldrich
5-Bromo-2-nitropyridine 99%
5g
$ 95.60

Matrix Scientific
5-Bromo-2-nitropyridine 98%
5g
$ 11.00

Labseeker
2-NITRO-5-BROMOPYRIDINE 95
500g
$ 415.00

Frontier Specialty Chemicals
2-Nitro-5-bromopyridine 98%
5g
$ 111.00

Crysdot
5-Bromo-2-nitropyridine 98%
500g
$ 176.00

Total 162 raw suppliers

Chemical Property of 5-Bromo-2-nitropyridine

Chemical Property:

Vapor Pressure:0.00323mmHg at 25°C
Melting Point:148-150 °C(lit.)
Refractive Index:1.614
Boiling Point:292.3 °C at 760 mmHg
PKA:-4.95±0.22(Predicted)
Flash Point:130.6 °C
PSA：58.71000
Density:1.833 g/cm³
LogP:2.27550
Storage Temp.:Inert atmosphere,Room Temperature
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:201.93779
Heavy Atom Count:10
Complexity:136

Purity/Quality:

99% ^*data from raw suppliers

5-Bromo-2-nitropyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=NC=C1Br)[N+](=O)[O-]
Uses 5-Bromo-2-nitropyridine is employed as a reagent in the synthesis of novel benzinidazoles, potent inhibitors of TIE-2 and VEGFR-2 Tyrosine (T899975) kinase receptors.

Technology Process of 5-Bromo-2-nitropyridine

There total 11 articles about 5-Bromo-2-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.8%

: 1072-97-5
5-bromo-2-pyridylamine

: 39856-50-3
5-bromo2-nitropyridine

Guidance literature:: With dihydrogen peroxide; In water; acetone; at 10 - 40 ℃; for 6h; Reagent/catalyst; Solvent; Temperature;

Reference yield: 49.1%

: 2402-97-3
3-bromopyridine N-oxide

: 39856-50-3
5-bromo2-nitropyridine

: 1678-49-5
3-Bromo-4-nitropyridine N-oxide

Guidance literature:: With sulfuric acid; nitric acid; at 0 - 90 ℃; for 5h;
DOI:10.14233/ajchem.2013.14356

Reference yield: 32.0%

: 30766-11-1
5-bromoisonicotinic acid

: 39856-50-3
5-bromo2-nitropyridine

Guidance literature:: With dipotassium peroxodisulfate; bismuth (III) nitrate pentahydrate; In acetonitrile; at 130 ℃; for 24h; Sealed tube;
DOI:10.1016/j.poly.2019.04.005