3-FLUOROMANDELIC ACID

Base Information

Chemical Name:3-FLUOROMANDELIC ACID
CAS No.:395-05-1
Molecular Formula:C₈H₇FO₃
Molecular Weight:170.14
Hs Code.:2918199090
Mol file:395-05-1.mol

Synonyms:3-Fluoromandelic acid;

Suppliers and Price of 3-FLUOROMANDELIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(3-Fluorophenyl)-2-hydroxyaceticacid 95+%
250mg
$ 85.00

Crysdot
2-(3-Fluorophenyl)-2-hydroxyaceticacid 95+%
1g
$ 240.00

American Custom Chemicals Corporation
3-FLUOROMANDELIC ACID 95.00%
25G
$ 1141.14

American Custom Chemicals Corporation
3-FLUOROMANDELIC ACID 95.00%
5G
$ 772.70

Alichem
2-(3-Fluorophenyl)-2-hydroxyaceticacid
1g
$ 185.40

Alichem
2-(3-Fluorophenyl)-2-hydroxyaceticacid
5g
$ 540.00

AK Scientific
3-Fluoromandelicacid
1g
$ 354.00

AK Scientific
3-Fluoromandelicacid
250mg
$ 134.00

Acrotein
3-Fluoro-a-hydroxy-benzeneaceticacid 97%
0.5g
$ 100.83

Total 22 raw suppliers

Chemical Property of 3-FLUOROMANDELIC ACID

Chemical Property:

Vapor Pressure:0.000149mmHg at 25°C
Melting Point:95.25 °C (heptane)
Boiling Point:318.6°Cat760mmHg
PKA:3.26±0.10(Predicted)
Flash Point:146.5°C
PSA：57.53000
Density:1.425g/cm³
LogP:0.94370
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

2-(3-Fluorophenyl)-2-hydroxyaceticacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-FLUOROMANDELIC ACID

There total 25 articles about 3-FLUOROMANDELIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 773837-37-9
sodium cyanide

: 456-48-4
3-Fluorobenzaldehyde

: 32222-47-2,52923-24-7,52950-14-8,395-05-1
2-(3-fluorophenyl)-2-hydroxyacetic acid

Guidance literature:: sodium cyanide; 3-Fluorobenzaldehyde; With benzyltrimethylammonium chloride; In diethyl ether; at 0 ℃; for 0.0833333h;

With hydrogenchloride; water; In diethyl ether; at 20 ℃; for 16h;

Reference yield: 32.0%

: 32222-47-2,52923-24-7,52950-14-8,395-05-1
2-(3-fluorophenyl)-2-hydroxyacetic acid

: 395-05-1,52923-24-7,52950-14-8,32222-47-2
(2R)-2-(3-fluorophenyl)-2-hydroxyacetic acid

Guidance literature:: With vinyl acetate; In tert-butyl methyl ether; at 26 ℃; for 90h; Enzymatic reaction;

Reference yield:

: 456-48-4
3-Fluorobenzaldehyde

: 32222-47-2,52923-24-7,52950-14-8,395-05-1
2-(3-fluorophenyl)-2-hydroxyacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 10percent aq. H₂SO₄ / ethanol / 7.9 °C

2: conc. aq. HCl / 19 h / Ambient temperature

With hydrogenchloride; sulfuric acid; In ethanol;
DOI:10.1107/S0108768193010766