1H-Imidazole-1-pentanamine

Base Information

• Chemical Name: 1H-Imidazole-1-pentanamine
• CAS No.: 78415-62-0
• Molecular Formula: C8H15N3
• Molecular Weight: 153.227
• DSSTox Substance ID: DTXSID50427965
• Wikidata: Q82240722
• Mol file: 78415-62-0.mol

Synonyms:1H-Imidazole-1-pentanamine;78415-62-0;5-imidazol-1-ylpentan-1-amine;5-(1H-imidazol-1-yl)pentan-1-amine;5-(1H-imidazol-1-yl)pentanamine;1-(5-aminopentyl)imidazole;SCHEMBL3173441;DTXSID50427965;5-(1H-imidazol-l-yl)pentanamine;JDBFAMNSPLNCHO-UHFFFAOYSA-N;5-(1H-imidazol-l-yl) pentanamine;MFCD06446894;AKOS002670916;NS-01185

Chemical Property of 1H-Imidazole-1-pentanamine

Chemical Property:

• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 153.126597491
• Heavy Atom Count: 11
• Complexity: 95.3

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN(C=N1)CCCCCN

Technology Process of 1H-Imidazole-1-pentanamine

There total 1 articles about 1H-Imidazole-1-pentanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(5-(1H-imidazol-1-yl)pentyl)isoindoline-1,3-dione (101225-92-7) → N-aminophthalamide (1875-48-5) + 5-(1H-imidazol-1-yl)pentanamine (78415-62-0)

Guidance literature:

With hydrogenchloride; hydrazine hydrate; Multistep reaction; 1.) EtOH, reflux, 8 h, 2.) EtOH, reflux, 6 h;

DOI:10.1021/jm00154a017

Reference yield: 82.0%

4-chloro-benzoyl chloride (122-01-0) + 5-(1H-imidazol-1-yl)pentanamine (78415-62-0) → 4-Chloro-N-(5-imidazol-1-yl-pentyl)-benzamide (93668-49-6)

Guidance literature:

With sodium hydroxide; In dichloromethane;

DOI:10.1021/jm00154a017

Reference yield: 81.0%

8-chloro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione (63497-60-9) + 5-(1H-imidazol-1-yl)pentanamine (78415-62-0) → 2-Amino-3-chloro-N-(5-imidazol-1-yl-pentyl)-benzamide (110552-64-2)

Guidance literature:

In tetrahydrofuran; Ambient temperature;

DOI:10.1021/jm00395a016

upstream raw materials:

2-(5-(1H-imidazol-1-yl)pentyl)isoindoline-1,3-dione

Downstream raw materials:

2-Amino-5-chloro-N-(5-imidazol-1-yl-pentyl)-benzamide

2-Amino-4-chloro-N-(5-imidazol-1-yl-pentyl)-benzamide

2-Amino-3-chloro-N-(5-imidazol-1-yl-pentyl)-benzamide

N-(5-Imidazol-1-yl-pentyl)-4-trifluoromethyl-benzamide