1H-Pyrrole-2-carboxamide, 4-[[(4-amino-1-methyl-1H-pyrrol-2-yl)carbonyl]amino]-N-[5-[[[3-(dimethyl amino)propyl]amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-

Base Information Edit

Chemical Name:1H-Pyrrole-2-carboxamide, 4-[[(4-amino-1-methyl-1H-pyrrol-2-yl)carbonyl]amino]-N-[5-[[[3-(dimethyl amino)propyl]amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-
CAS No.:78486-18-7
Molecular Formula:C23H32N8O3
Molecular Weight:468.559
Hs Code.:
Mol file:78486-18-7.mol

1H-Pyrrole-2-carboxamide,
4-[[(4-amino-1-methyl-1H-pyrrol-2-yl)carbonyl]amino]-N-[5-[[[3-(dimethyl
amino)propyl]amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-

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Chemical Property of 1H-Pyrrole-2-carboxamide, 4-[[(4-amino-1-methyl-1H-pyrrol-2-yl)carbonyl]amino]-N-[5-[[[3-(dimethyl amino)propyl]amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl- Edit

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MSDS Files:: SDS file from LookChem

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Technology Process of 1H-Pyrrole-2-carboxamide, 4-[[(4-amino-1-methyl-1H-pyrrol-2-yl)carbonyl]amino]-N-[5-[[[3-(dimethyl amino)propyl]amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-

There total 1 articles about 1H-Pyrrole-2-carboxamide, 4-[[(4-amino-1-methyl-1H-pyrrol-2-yl)carbonyl]amino]-N-[5-[[[3-(dimethyl amino)propyl]amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 77716-11-1
4-[(tert-butoxycarbonyl)amino]-1-methyl-1H-pyrrole-2-carboxylic acid

: 78486-18-7
3-(1-methyl-4-(1-methyl-4-(1-methyl-4-aminopyrrole-2-carboxamido)pyrrole-2-carboxamido)pyrrole-2-carboxamido)dimethylaminopropane

Guidance literature:: Multi-step reaction with 4 steps

1.1: 4.3 mg / EDCI; DMAP / dimethylformamide / 16 h / 25 °C

2.1: 98 percent / aq. LiOH / tetrahydrofuran; methanol / 8 h / 60 °C

3.1: EDCI; DMAP / dimethylformamide / 1 h / 25 °C

3.2: 68 percent / dimethylformamide / 13 h / 25 °C

4.1: HCl / ethyl acetate / 1 h / 25 °C

With hydrogenchloride; dmap; lithium hydroxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; methanol; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/ja994192d