1-Propanone, 1-(4-aminophenyl)-2-chloro- (9CI)

Base Information

• Chemical Name: 1-Propanone, 1-(4-aminophenyl)-2-chloro- (9CI)
• CAS No.: 25021-66-3
• Molecular Formula: C9H10 Cl N O
• Molecular Weight: 183.6348
• Hs Code.: 2922399090
• Mol file: 25021-66-3.mol

Synonyms:Propiophenone,4'-amino-2-chloro- (8CI); 1-(4-Aminophenyl)-2-chloropropanone;2-Chloro-4'-aminopropiophenone; NSC 281615; a-Chloro-p-aminopropiophenone

Chemical Property of 1-Propanone, 1-(4-aminophenyl)-2-chloro- (9CI)

Chemical Property:

• Vapor Pressure: 7.48E-05mmHg at 25°C
• Boiling Point: 342.5°Cat760mmHg
• Flash Point: 161°C
• PSA: 43.09000
• Density: 1.211g/cm³
• LogP: 2.66000

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Propanone, 1-(4-aminophenyl)-2-chloro- (9CI)

There total 4 articles about 1-Propanone, 1-(4-aminophenyl)-2-chloro- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.7%

pyrographite (7440-44-0) + N-[4-(2-chloro-1-oxopropyl)phenyl]acetamide (81112-08-5) → 1-(4-aminophenyl)-2-chloropropanone (25021-66-3)

Guidance literature:

In benzene;

Reference yield:

Acetanilid (103-84-4) → 1-(4-aminophenyl)-2-chloropropanone (25021-66-3)

Guidance literature:

Multi-step reaction with 2 steps

1: carbon disulfide; aluminium trichloride

With carbon disulfide; aluminium trichloride;

Reference yield:

N-(4-(2-bromopropionyl)phenyl)acetamide (63514-63-6) → 1-(4-aminophenyl)-2-chloropropanone (25021-66-3)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

N-(4-(2-bromopropionyl)phenyl)acetamide

hydrogenchloride

Acetanilid

pyrographite

Downstream raw materials:

4-(5-methyl-2-p-tolyl-thiazol-4-yl)-aniline

4-[2-(3,4-dimethoxy-phenyl)-5-methyl-thiazol-4-yl]-aniline

4-(2,5-dimethyl-thiazol-4-yl)-aniline

1-(4-amino-3,5-dichlorophenyl)-2-chloropropanone