2,3,4,6-Tetramethoxybenzoic acid

Base Information

Chemical Name:2,3,4,6-Tetramethoxybenzoic acid
CAS No.:6342-81-0
Molecular Formula:C₁₁H₁₄O₆
Molecular Weight:242.229
Hs Code.:
NSC Number:46650
DSSTox Substance ID:DTXSID60286606
Wikidata:Q82022379

Synonyms:2,3,4,6-tetramethoxybenzoic acid;6342-81-0;NSC 46650;NSC46650;DTXSID60286606;NSC-46650

Suppliers and Price of 2,3,4,6-Tetramethoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2,3,4,6-Tetramethoxybenzoic acid

Chemical Property:

Vapor Pressure:6.09E-06mmHg at 25°C
Boiling Point:364.2°Cat760mmHg
Flash Point:138°C
Density:1.223g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:242.07903816
Heavy Atom Count:17
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C(=C1C(=O)O)OC)OC)OC

Technology Process of 2,3,4,6-Tetramethoxybenzoic acid

There total 9 articles about 2,3,4,6-Tetramethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

: 124-38-9,18923-20-1
carbon dioxide

: 5333-45-9
1,2,3,5-tetramethoxybenzene

: 6342-81-0
2,3,4,6-tetramethoxybenzoic acid

Guidance literature:: 1,2,3,5-tetramethoxybenzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

carbon dioxide; In tetrahydrofuran; Inert atmosphere;
DOI:10.1139/v11-087

Reference yield:

: tetramethoxy-isophthalic acid

: 6342-81-0
2,3,4,6-tetramethoxybenzoic acid

Guidance literature:: With copper; at 195 ℃; Erhitzen unter vermindertem Druck;

Reference yield:

: 86-81-7
3,4,5-trimethoxy-benzaldehyde

: 6342-81-0
2,3,4,6-tetramethoxybenzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / Inert atmosphere

2.1: water; potassium hydroxide / tetrahydrofuran / Inert atmosphere

3.1: potassium carbonate / acetone / Inert atmosphere

4.1: n-butyllithium / tetrahydrofuran / -78 °C / Inert atmosphere

4.2: Inert atmosphere

With n-butyllithium; water; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; potassium hydroxide; In tetrahydrofuran; dichloromethane; acetone; 1.1: Baeyer-Villiger oxidation;
DOI:10.1139/v11-087