Carbamic acid, [2-[3-iodo-4-(phenylmethoxy)phenyl]ethyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [2-[3-iodo-4-(phenylmethoxy)phenyl]ethyl]-, 1,1-dimethylethyl ester
CAS No.:788824-73-7
Molecular Formula:C20H24INO3
Molecular Weight:453.32
Hs Code.:
DSSTox Substance ID:DTXSID901131104

Synonyms:SCHEMBL4458132;DTXSID901131104;Carbamic acid, [2-[3-iodo-4-(phenylmethoxy)phenyl]ethyl]-, 1,1-dimethylethyl ester;788824-73-7

Suppliers and Price of Carbamic acid, [2-[3-iodo-4-(phenylmethoxy)phenyl]ethyl]-, 1,1-dimethylethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Carbamic acid, [2-[3-iodo-4-(phenylmethoxy)phenyl]ethyl]-, 1,1-dimethylethyl ester

Chemical Property:

XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:453.08009
Heavy Atom Count:25
Complexity:404

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCC1=CC(=C(C=C1)OCC2=CC=CC=C2)I

Technology Process of Carbamic acid, [2-[3-iodo-4-(phenylmethoxy)phenyl]ethyl]-, 1,1-dimethylethyl ester

There total 5 articles about Carbamic acid, [2-[3-iodo-4-(phenylmethoxy)phenyl]ethyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 788824-50-0
[2-(4-hydroxy-3-iodo-phenyl)-ethyl]-carbamic acid tert-butyl ester

: 100-39-0
benzyl bromide

: 788824-73-7
N-t-butoxycarbonyl-O-benzyl-3-iodotyramine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/jm0505718

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 788824-73-7
N-t-butoxycarbonyl-O-benzyl-3-iodotyramine

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / aq. NaHCO₃ / tetrahydrofuran / 24 h

2: 55 percent / NaI; KOH; NaOCl / methanol / 4 h / 0 °C

3: 78 percent / K₂CO₃ / dimethylformamide / 20 °C

With potassium hydroxide; sodium hypochlorite; sodium hydrogencarbonate; potassium carbonate; sodium iodide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0505718

Reference yield:

: 64318-28-1
N-t-butoxycarbonyl-tyramine

: 788824-73-7
N-t-butoxycarbonyl-O-benzyl-3-iodotyramine

Guidance literature:: Multi-step reaction with 2 steps

1: 55 percent / NaI; KOH; NaOCl / methanol / 4 h / 0 °C

2: 78 percent / K₂CO₃ / dimethylformamide / 20 °C

With potassium hydroxide; sodium hypochlorite; potassium carbonate; sodium iodide; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0505718